PubMed Health⌕ Search

Biomedical subjects

P Martin-Noel

Publications and source records attributed to P Martin-Noel.

At least 19 recordsLinked to original sources

[Aortic and tricuspid valve involvement caused by myxoid degeneration associated with a severe mitral prolapse. Apropos of 2 patients undergoing a double valve replacement].

Idiopathic mitral valve prolapse due to severe myxoid degeneration may be associated with aortic and/or tricuspid valve disease of the same aetiology. These localisations, which usually give rise few symptoms, can be detected by echocardiography. Sometimes, however, they may give rise to serious valvular regurgitation requiring surgical correction at each diseased valve. The authors report two cases of "floppy" mitral valve prolapse, the first requiring mitral and tricuspid, and the second, mitral and aortic, valve replacement. These cases underline the value of especially by echocardiography, in view of their serious complications.

Adult↗

[Diagnosis of limited septal infarction associated with a posterior or postero-inferior infarction. Value of vectorcardiography and clinical, coronary angiographic and developed correlations].

In patients with posterior or postero inferior infarction, a limited septal infarction may be detected by vectorcardiography, septal extension being a sign of disease of the left anterior descending artery. In order to confirm this hypothesis, 31 posterior or postero inferior infarction with septal extension were selected by vectorcardiography from more than 500 ECGs recorded after the acute phase of a clinically and biologically documented infarction. The following criteria were chosen: 1. Anterior deviation of the QRS, associated or not with superior deviation of the initial deflection lasting over 25 ms and clockwise rotation of the frontal loop (posterior infarct: 9 cases, postero inferior infarct: 22 cases). 2. Abnormalities of the initial phase of the QRS in the horizontal plane, associated with a reduced amplitude and duration of the initial deflection. The clinical, ECG, vectorcardiographic and angiographic (14 cases) features of these 31 postero septal infarcts were compared with those of 31 posterior septal infarcts were compared with those of 31 posterior or postero inferior infarcts (24 coronary angiographies). 1. From the clinicl point of view, in the acute phase postero septal infarction did not differ from posterior infarction and the early prognosis was favourable. On the other hand, with an average follow-up of 2 years, the outcome of postero septal infarction was statistically more complicated than that of strict posterior infarction (52 p. 100 compared to 19 p. 100, p < 0.01). 2. From the electrocardiographical point of view, septal extension of posterior infarction was only suspected in 25 p. 100 cases. In the acute phase, ST depression in V2 to V5 sometimes associated with reduction of the R wave in the right precordial leads and QS waves in V4R, suggesting a "rudimentary" or "subendocardial" infarct. 3. From the angiographic point of view, although disease of the posterior vessels was equally common in posterior and postero septal infarction (86 p. 100 compared to 92 p. 100 NS), stenosis of the left anterior descending artery was statistically more common in postero septal infarction than in posterior infarction (86 p.100 compared to 29 p. 100, p < 0.001). Thallium myocardial scintigraphy, when performed, showed the double myocardial lesion in the antero septal and postero inferior walls in postero septal infarction. These results validate the vectorcardiographical criteria retained for diagnosis of postero septal infarction and confirmed the superiority of the vectorcardiogramme over the electrocardiogramme in the diagnosis of double infarction. Therefore, the vectorcardiogramme in the diagnosis of double infarction. Therefore, the vectorcardiogramme allows selection of the patients with postero diaphragmatic infarction with a limited septal extension, for whom coronary angiography should be proposed. A "postero septal" infarct diagnosed on vectorcardiogramme has a high probability of stenosis of the left anterior descending artery.

Coronary Angiography↗

[Dromotropic effects of drug combinations. Initial results bearing on a combination of deslanoside and ajmaline].

The electrophysiological effects of the cardiotropic drugs have been studied in man by the agency of endocavitary electrocardiography. The effects of drug combinations, which are often prescribed therapeutically, have been studied less often. The authors report the results of a preliminary study of the combination of deslanoside with ajmaline in 26 patients; its effects were compared with those using each drug separately. This combination seems to have true dromotropic effects; although deslanoside alone, in the doses used, does not modify conduction below the bundle of His, it can still act synergistically with ajmaline at this level. A detailed study of the pharmacological effects as a function of the original status of conduction shows that at the level above the bundle His, the dromotropic action is quantitively less on healthy conducting tissue than on abnormal tissue. The effects of ajmaline on the conduction times below the bundle seem to be similar whether or not there is any conduction defect under basal conditions. The difficulties in obtaining and interpreting such measurements in man are discussed in the hope of arriving at a general protocol for studying drug combinations.

Adult↗

[Recording of the cardiac magnetic field. Technical considerations and initial results in hospital practice].

Recording the magnetic field of the heart poses enormous technical problems. Whatever type of captor is used, the parasite magnetic fields are 11000x more powerful than those of cardiac origin, and must be excluded. It is for this reason that magnetocardiography has remained a laboratory technique until the last few years. The authors present an induction magnetocardiograph whose specifications make it suitable for use in hospital practice. Thanks to the selectivity of the captor, it is possible to produce magnetic plots of the thorax.

Electrocardiography↗

[Rupture of the tricuspid cordae simulating a right intraventricular tumor].

Ruptured chordae tendinae of the tricuspid valve is exceptional. It results in an intense valvular incompetence through systolic eversion of one leaflet. In fact, this is not always the case, and in patient reported, the clinical picture suggested an obstacle to right ventricular ejection with paroxysmal phenomena of the faintness type, indicating the temporary obstruction of the pulmonary pathway. Right cine-angiocardiography demonstrated a mobile intraventricular neoformationreaching in systole the pulmonary sub-valvar area. No tumour was found on operation. The patient died in the post-operative period. On post-mortem examination there was a rupture of tricuspid chordae tendinae and a raise of the anterior leaflet of the tricuspid valve into the pulmonary infundibulum. Rupture could be related to a severe thoracic trauma which had occurred 17 years previously.

Cardiomegaly↗

[Myxoma of the left ventricle. Apropos of a successfully operated case].

Left ventricular myxomata are exceptional (12 published cases). In the case reported, the clinical picture included emboli (cerebral and coronary) and syncope. Auscultation, the electrocardiogram and the phonomechanocardiographic tracings suggested an impaired left ventricular ejection, while the left ventriculography demonstrated the tumour and the coronary arteriography its vascular relationship with the right coronary artery. Cure was obtained by surgical removal. In that respect, an attempt was made to describe the clinical and paraclinical bases for the diagnosis of the myxomata of the left ventricle.

Child↗

[Chronic pericardial effusion and congenital cardiopathy].

Report of one case of chronic pericardial effusion combined with pulmonary valve stenosis and atrial septal defect in a man aged 31, hospitalized for congestive heart failure. The relationship between these two diseases were studied, and the diagnostic and therapeutic problems posed were studied.

Adult↗