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Biomedical subjects

P Mathieu

Publications and source records attributed to P Mathieu.

At least 235 records · Page 13Linked to original sources
PubMed1976

[Venous signs at the acute stage of pulmonary embolism].

The authors have carried out phlebograms on 50 patients with recent pulmonary emboli. In the majority of cases (44 out of 50) they found thrombosis in the veins of the lower limbs: in 35 cases, these were situated proximally, ending in the femoro-ilio-caval segment; in 9 cases they were confined to the suropopliteal veins. These facts have led us to modify our treatment plan for pulmonary embolism. Thrombolytic treatment seems to be justified in cases where the prebitis is high up, even if the pulmonary embolus is benign. Heparin is reserved for those cases of benign pulmonary emboli which are secondary to suro-popliteal phlebitis. The question of interrupting the inferior vena cava must bed ecided in the light of the phlebograms.

Acute Disease↗
PubMed1976

[Development of pulmonary embolism].

The authors have made a study of the fate of 118 patients with pulmonary embolism. The mortality (21.8%) is related not only to the embolus itself (especially to the recurrent types) but also to the condition of the affected area. Recurrence is common (34%), serious (9 deaths out of 25), and early (during the first three months.). No treatment or inadequate treatment are the main causes. Treatment works effectively on the pulmonary circulation, which becomes reestablished in the majority of cases, but it carries the risk of a high incidence of haemorrhage (29%) which is severe (2 deaths and 10 tranfusions of more than one litre of blood). In the long term, the prognosis is linked to the developments in the lower limbs, in which there is a progressive failure of venous drainage (46 cases out of 57), even in cases in which there was no local sign of phlebitis at the time of the original embolus.

Adult↗
PubMed1976

["Habitual" left branch block alternating with 2 "disguised" bracnch block].

Two cases of alternating left bundle branch block and "masquerading block" (with left bundle branch morphology in the stnadard leads and right bundle branch block morphology in the precordial leads) were studied by serial tracings and his bundle electrocardiography. In case 1 "the masquerading" block was associated with a first degree AV block related to a prolongation of HV interval. This case is to our knowledge the first cas of alternating bundle branch block in which his bundle activity was recorded in man. In case 2, the patient had atrial fibrilation and His bundle recordings were performed while differents degrees of left bundle branch block were present: The mechanism of the alternation and the concept of "masquerading" block are discussed. It is suggested that this type of block represents a right bundle branch block associated with severe lesions of the "left system".

Aged↗
PubMed1975

[Respective value of labelled fibrinogen and rheography in the detection of phlebitis].

The authors have studied in 212 patients the diagnostic value of radio-active fibrinogen and rheography in deep venous thrombosis of the leg by comparing the results from these two methods with phlebography. Radio-active fibrinogen seems the better means of diagnosis in early distal phlebitis. However, the method is expansive, the radio-active substance can only be manipulated in certain specialized centers, and is useless in the presence of hematoma. Rheography is less expansive, more easily manipulated, yet less sensitive as only proximal phlebitis can be detected-especially when completely occlusive. In addition, active patient cooperation is necessary. The time needed to realize the two methods is a major obstacle; however, they can be fruitful if integrated into a specialized department for the diagnosis and treatment of thrombo embolic disease.

Collateral Circulation↗
PubMed1975

[Pre-infarction syndrome involving the anterior interventricular artery. Therapeutic and diagnostic considerations].

Based on the study of 25 cases, the authors define menace syndrome in the anterior descending artery (ADA) according to three criteria: angina of recent onset and rapid development, a major disorder of repolarisation in the anterior part of the heart, and a tight proximal stenosis of the ADA. Of seven patients who could not undergo surgery, three sustained anterior infarctions, and three died after 30 days. 18 patients underwent surgery to revascularise the myocardium by anastomosis of the internal mammary artery to the ADA; 13 of these were carried out as urgent procedures (an average of 26 hours after coronary arteriography). The functional results were excellent, and all of the internal mammary anastomoses studied at 6 months (9 cases) were patent. This study has shown that menace syndrome of the ADA is a surgical emergency, and that a procedure to anastomose the coronary arteries should be carried out immediately after coronary anteriography.

Adult↗