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Biomedical subjects

P Matin

Publications and source records attributed to P Matin.

At least 19 recordsLinked to original sources
PubMed1988

Basic principles of nuclear medicine techniques for detection and evaluation of trauma and sports medicine injuries.

Nuclear medicine skeletal imaging is a very sensitive technique for evaluating bone and muscle abnormalities because it can detect minor changes in metabolism and blood flow. The specificity of bone imaging, however, depends on the ability of the nuclear medicine physician to make a differential diagnosis. To aid in making a specific diagnosis, this article describes the various patterns of abnormality in stress fractures, tibial stress syndrome (shin splints), compartment syndrome, enthesopathy, and traumatic fractures. The characteristic scintigraphic appearance of joint injuries, muscle injuries (rhabdomyolysis), and radionuclide arthrography is discussed and the way the scan patterns change with time in these various disorders is described. A brief summary of the basic anatomy and physiology of bone and muscle in normal and injured tissue is presented and the basic mechanisms which cause the various abnormal scan patterns is postulated. In addition, a staging system for stress fractures is presented to help direct the referring physician toward the proper management of the injured patient. In most cases, nuclear medicine skeletal imaging can be used to differentiate between acute muscle injury, tibial stress syndrome, skeletal injury (periosteal reaction, stress fracture, and traumatic fracture) or an abnormality that is entirely associated with the joint or connective tissue. This differential diagnosis is easier if the nuclear medicine procedure is performed within a few days after the onset of injury.

Athletic Injuries↗
PubMed1983

Bone scintigraphy in the diagnosis and management of traumatic injury.

Imaging with bone-seeking nuclear medicine radiopharmaceuticals has changed dramatically in a span of 10 years. The only indication for bone scintigraphy a decade ago was to detect skeletal metastases in patients with known carcinoma. Improvements in equipment and radiopharmaceuticals have led to the use of nuclear medicine studies for the detection and evaluation of a multitude of benign abnormalities. This article discusses the use of bone-seeking radiopharmaceuticals in traumatic processes involving the skeletal system, connective tissues, and muscles. A review of the subject is included, as well as some new ideas regarding the interpretation and evaluation of scintigraphs with respect to trauma to the bones and soft tissues.

Adolescent↗
PubMed1983

Scintigraphic evaluation of muscle damage following extreme exercise: concise communication.

Total body Tc-99m pyrophosphate scintigraphy was performed on 11 "ultramarathon" runners to assess the ability of nuclear medicine techniques to evaluate skeletal-muscle injury due to exercise. We found increased muscle radionuclide concentration in 90% of the runners. The pattern of muscle uptake correlated with the regions of maximum pain. The detection of exercise-induced rhabdomyolysis appeared to be best when scintigraphy was performed within 48 hr after the race, and to be almost undetectable after about a week. It was possible to differentiate muscle injury from joint and osseous abnormalities such as bone infarct or stress fracture. Although 77% of the runners had elevated serum creatine kinase MB activity, cardiac scintigraphy showed no evidence of myocardial injury.

Adult↗
PubMed1979

The appearance of bone scans following fractures, including immediate and long-term studies.

Bone scans were performed on 204 patients at intervals ranging from 6 hr to several years after traumatic fractures. The minimum time for a bone scan to become abnormal following fracture was age-dependent; however, 80% of all fractures were abnormal by 24 hr, and 95% by 72 hr, after injury. Three distinct temporally related phases were noted on bone scans as sequential studies showed a gradual return to normal. The minimum time for a fracture to return to normal on a bone scan was 5 mo. Approximately 90% of the fractures returned to normal by 2 yr after injury.

Adolescent↗
PubMed1978

A review of carotid cavernous fistula including diagnosis and evaluation by nuclear medicine angiography.

The various causes and differential diagnosis of carotid cavernous fistula are discussed as well as the description of the use of radionuclide angiography in the diagnosis and evaluation of patients with carotid cavernous fistulas. Radionuclide angiography has proven extremely useful in the diagnosis and follow-up of patients with carotid cavernous fistulas. The procedure is of maximum benefit in situations where repeat studies are required at frequent intervals. Five cases are described in which the nuclear medicine technique was instrumental in primary diagnosis and follow-up.

Adult↗