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Biomedical subjects

P Mazumdar

Publications and source records attributed to P Mazumdar.

8 recordsLinked to original sources
PubMed2001

Dermatoglyphic analysis in Malay subjects with bipolar mood disorder.

Dermatoglyphic is the study of the epidermal ridges and the pattern formed by them. It may be pointed out that genetic factors have a large share in determining the variations in dermatoglyphics. It is however, suggested by evidence that bipolar mood disorder factors are determined more by genetic factors than by the environmental factors. The experiment has been undertaken to look for the effects of the bipolar mood disorder on dermatoglyphics. The dermatoglyphic characteristics of subjects with bipolar mood disorder when compared with control group revealed significant differences. The radial loop were increased in bipolar mood disorder, but there were little changes in 'atd' angles between normal and bipolar mood disorder.

Bipolar Disorder↗
PubMed2000

New developments in schizophrenia.

BACKGROUND: Over 2% of the population suffer from schizophrenia and related psychoses. Virtually all sufferers now live in the community, and go to see their general practitioners. OBJECTIVE: To overview recent developments in the presentation and causes of schizophrenia and its treatment with medication and psychosocial intervention. DISCUSSION: The diagnostic boundaries of schizophrenia have become less distinct as aetiological and therapeutic similarities between schizoaffective and affective psychoses have emerged. The importance of specific symptom groups (positive, negative, cognitive, manic, depressed) with respect to brain mechanisms and response to treatment has been recognised. It is now thought that recognition of early phase illness and vigorous treatment aimed at relapse prevention may improve long term prognosis. Availability of new medications has improved outcomes. Patients with schizophrenia living in the community need a range of services best delivered through collaborative care between GPs, community and specialist services.

Antipsychotic Agents↗
PubMed2000

The new antipsychotics. How much better are they?

BACKGROUND: Despite considerable efficacy, conventional antipsychotics cause debilitating extrapyramidal side effects and may worsen 'negative' symptoms of schizophrenia. New atypical antipsychotics (clozapine, risperidone, olanzapine) have become available, and quetiepine is expected shortly; it is TGA approved and is currently available to psychiatrists through a familiarization program. OBJECTIVE: To inform general practitioners about the novel antipsychotics and their therapeutic role in contrast to conventional antipsychotic drugs. DISCUSSION: The major benefit offered by atypical antipsychotics is that these drugs are less likely to cause distressing and disabling extrapyramidal side effects at therapeutically effective doses than conventional drugs. Advantages in terms of efficacy are marginal, though clozapine is superior to conventional drugs in treatment resistant patients. The new drugs are not without other side effects. Clozapine can cause agranulocytosis, needs ongoing haematological monitoring and is only available through specialist centres. However, the new drugs do improve overall outcome. Use of risperidone, olanzapine and quetiepine is now widely recommended in preference to conventional drugs, while clozapine is used when other drugs have failed.

Antipsychotic Agents↗
PubMed1992

Seasonal relapses in affective disorder in the Tropics: a prospective follow-up of 12 patients.

Seasonal relapses of affective disorder are known. We report 12 patients who had season-linked relapses during a prospective follow-up period of 4 years. There were both winter and summer relapses of mania and depression. The centre is in the tropical zone, with lesser variation of sunshine and temperature than in more extreme latitudes. This may inference the pattern of relapse in affective disorder. Differences in relapses between tropical and temperate zones need to be investigated.

Adult↗
PubMed1991

Heart rate & blood lactate response in field hockey players.

The heart rate and blood lactate were studied in field hockey players (25 juniors and 29 seniors) as well as the blood lactate response in training to assess the anaerobic demand of the game and the adaptability of the players to anaerobic metabolism, respectively. The mean VO2 max of the junior and senior players were 3.32 l/min (54.4 ml/kg/min) and 3.28 l/min (53.8 ml/kg/min), respectively. Blood lactate levels after warm up, training and the game were 2.1, 7.4 and 4.2 mM/l, respectively for the juniors and 2.6, 7.7 and 5.6 mM/l, for the seniors. The aerobic capacity (VO2 max) of the juniors did not differ from their senior counterparts, indicating a similar adaptability to aerobic metabolism. However, the Indian players revealed a lower VO2 max than their International counterparts. Similar lactate levels in juniors and seniors after training indicated a similar adaptability to the anaerobic metabolism also. The higher blood lactate level in seniors after the game reflected that they played with greater intensity than the juniors, due to more experience, better motivation and skill.

Adolescent↗
PubMed1966

Wilm's tumour.

Explore the source record for details and available documents.

Child↗