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Biomedical subjects

P Mazure

Publications and source records attributed to P Mazure.

6 recordsLinked to original sources
PubMed1985

[Plasma clearance of alpha 1-antitrypsin. A simple method for the study of intestinal protein loss].

We tried to evaluate the value of the alpha-1-antitrypsin clearance in order to search for the protein loss through the digestive tract. Twenty-two patients were studied, 11 with protein losing enteropathy and 11 normal controls. Alpha-1-antitrypsin concentration was determined in serum and feces to obtain the clearance of such protein. The values were always abnormal in patients with protein losing enteropathy, and normal in control patients. We consider this method simple and safe for the evaluation of intestinal protein loss, besides having the advantage of not using radioactive material.

Feces↗
PubMed1978

[Achalasia of the esophagus].

Thirty-two cases of achalasia of the esophagus are studied in retrospect. The evolution was carried on from different standpoints: clinical, radiological, endoscopic, and motility studies. Patients were treated by dilatation (either pneumatic or mercury bougies) or surgery. The result of treatment was evaluated from the clinical standpoint correlating it with the remaining studies in order to establish wether or not they were related.

Dilatation↗
PubMed1978

[Effect of hydrochlorothiazide on acid secretion and potassium and sodium in the human gastric mucosa].

Hydrochlorotiazide induced changes of gastric acid secretion, Sodium (Na) and potassium (K) of human gastric mucosa". In ten patients with elevated acid secretion we determined maximal acid secretion after histamine stimulation, Na and K in serum and in fundic mucosa obtained by peroral gastric biopsy. These experiments were performed before and after the oral administration of hydrochlorotiazide (200 mg/day) during seven days. After diuretic treatment we observed a significant decrease of Na (P less than 0.01) and K (p less than 0.05) in gastric mucosa. Both ions also decreased significantly in plasma (p less than 0.01). In gastric juice the decrease was significant for volume and peak acid output (p less than 0.01) and for total acidity (p less than 0.05). The significance of these findings is discussed.

Adult↗