PubMed Health⌕ Search

Biomedical subjects

P McMichael

Publications and source records attributed to P McMichael.

4 recordsLinked to original sources

The impact of globalisation, free trade and technology on food and nutrition in the new millennium.

The millennium promises a dramatic politicisation of the food question. In addition to the prominent issues of food security, hunger and nutrition, bioengineering, food safety and quality, there are related issues of environmental sustainability, power, sovereignty and rights. All these issues are deeply implicated in the current corporate form of globalisation, which is transforming historic global arrangements by subordinating public institutions and the question of food security to private solutions. The present paper questions the self-evident association between globalisation and nutritional improvement.

Biotechnology↗

Crystallization and preliminary X-ray studies on Candida cylindracea lipase.

As part of the programme to understand the mechanism and specificity of lipase enzymes used in biotransformation reactions, the lipase from Candida cylindracea has been purified and crystallized. This lipase has been widely used by organic chemists for hydrolysis and esterification reactions. Crystals were obtained using polyethylene glycol 6000 as a precipitant and grew to 0.6 mm in the maximum dimension. The enzyme crystallized in the space group P2(1) with unit-cell dimensions a = 94.3, b = 117.0, and c = 114.2 A with beta = 109.2 degrees. Calculations indicate that there are four molecules in the asymmetric unit. The crystals diffract to at least 2.5 A resolution and the structure has been solved by molecular replacement using the lipase from Geotrichum candidum as a search model.

Journal Article↗