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Biomedical subjects

P Meriel

Publications and source records attributed to P Meriel.

At least 19 recordsLinked to original sources

[Localized tetanus after esophagogastrectomy].

Post-operatory partial tetanus is a more and more rare event. It can outcome after any type of surgery but especially after abdominal surgery. The contamination is usually endogenous through the digestive bacteria and it develops in anaerobic context. These different factors were united in this report. The diagnosis is difficult if not keep in mind. The treatment is usual, but prevention might be pointed out.

Esophagus

[Transfer of CO after prolonged artificial ventilation (18 young people after their stay in the neuro-surgery department) (author's transl)].

We studied the transfer of CO (TLCO) on 18 young people after their stay in the neuro-surgery department, during which they had been submitted to prolonged artificial ventilation. The values of TLCO measured after the single breath method and that of the steady state are all reduced. No statistical correlation has been brought to light between the length of artificial ventilation, or the FiO2 and the lowering of TLCO, or between the seriousness of the pulmonary complications which occurred and the disturbance of the pulmonary function test. To explain the change of the alveolo-capillary diffusion, different factors can be brought in, such as: artificial ventilation, the toxicity of oxygen, the adult respiratory distress syndrome, but also the presence of brain lesions which by reflex artery, modify the local hemodynamic conditions and the surfactant synthesis.

Adolescent

[Use of sodium nitroprusside in otological surgery (author's transl)].

The authors report on the experiment carried out on the use of sodium nitroprusside (NPS) in otological surgery. The acknowledged advantages of NPS over hypotensors and more particularly its spécifically vascular, périphéral, swift action, rapidly reversible, are worth mentioning. Control over the achieved hypotension however, requires careful attention to avoid overdosage which could result in severe hypotension and "cyanhydric" intoxication. The recording of capillary pulse constitutes an easy and reliable solution to the difficulties arising from permanent control of blood-pressure and of peripheral arterial perfusion. The method both produces excellent results permitting bloodless surgery, and allows a reduction of NPS doses giver, without resorting to a invasive for measuring blood pressure. The method used in surgical fields other than otology has already proved very satisfactory.

Capillaries

[Diabetes mellitus in pheochromocytoma].

The frequency of latent disorders of glucose regulation during pheochromocytoma, is evaluated at 75% of cases. Detailed analysis of 83 cases with a diabetic state, gave the following results: insulin dependent diabetes, 37 cases. Non-insulin dependent, 14 cases. Latent diabetes, 32 cases. The characteristics of the insulin-dependent diabetes were not always suggestive. Insulin dependency was, however, unusual above a certain age. We noted loss of weight in spite of good control of the diabetes, the absence of acidosis and ketosis contrasting with rapid loss of weight. In fact, it is above all the hypertension which should lead to diagnosis. Surgical operation, cures or improves considerably the diabetic state, thus proving the symptomatic nature of this diabetes.

Catecholamines

[Combination of R3365 (piritramide) and dehydrobenzperidol in animals. Respiratory effects and analgesia].

1 -- Respiratory depression has been studied in the no anaesthetized rabbit by analysis of the blood gases after an injection of Piritramide (R 3365) and dehydrobenzperidol. 2 -- The respiratory depression induced by Piritramide alone is less important after an injection of dehydrobenzperidol; the most interessant cases are: -- mixture dehydrobenzperidol 400 mug/kg. Pirittramide 1000 mug/kg; --dehydrobenzperidol (400 mug/kg) injected 15 minutes before Piritramide (1000 mug/kg). 3 -- The addition of Dehydrobenzperidol does not take the analgesic activity of Piritramide decrease by it increases it.

Analgesics