[Dysphagia lusoria caused by aberrant left subclavian artery and Kommerell diverticulum].
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Biomedical subjects
Publications and source records attributed to P Moratinos Palomero.
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We have tested de possible protective effects of UVA radiated spleen fragments upon simultaneous skin allografts in 84 rats. Under these circumstances skin graft rejection was less evident with a 20 day graft disappearance rate of 46.87% rate in the treated series, that compares favourably with a 80% in the control series. This study shows a parallel increase in the mean survival time of skin grafts in treated specimens. The figures being 19.8 days in the treated series against 12.9 days in untreated controls. Spleen implants are finally shown to produce a healing stimulus in the skin graft zone. These differences are statistically significant.
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A study was carried out on 40 dogs. Four groups of ten dogs each were established. A laparotomy group, a simple splenectomy group and two groups which underwent a selective autotransplant of the medium an deep layers of a centrifugated solution of splenic medulla respectively. Immunisation with BSA showed that humoral immune response with formation of anti-BSA antibodies is more intense in the control group which underwent laparotomy than in the splenectomised group. The response obtained in dogs subjected to autotransplant of deep layer is almost identical to that of the control group while that of the medium layer showed a slightly lower response. Cellular immune response is more accentuated in the group which underwent autotransplant from the deep layer, while those from the medium layer showed a higher response than that of the splenectomised group.
Primary and secondary humoral immune responses were studied in a group of 40 dogs after splenectomy and two types of splenic autotransplantation. The results enable the authors to conclude that splenectomy alone induces a depletion of immunoglobulins which is statistically significant. On the other hand, both types of autotransplantation made possible the maintenance of normal levels of anti-BSA antibodies. When autotransplantation was performed in the abdominal rectus muscle there was an enhancement of the primary immune response. The authors advise this procedure in all splenectomies for trauma in the first five years of life.
A case of Letterer-Siwe revealing the clinical variability of this illness is described. A one and a half year old child with osteoporosis and osteolysis of the sphenoid bone at the level of the sella turcica and eczematous lesions in the retroauricular and cranial region is presented. Cortical steroid and orally administered Methotrexate have been used. Progress is good and possibility of radiating the sphenoid bone lesion with a small field not affecting the hypophysis is considered.