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Biomedical subjects

P Moshchin'ski

Publications and source records attributed to P Moshchin'ski.

4 recordsLinked to original sources
PubMed1990

[Humoral immunity in smokers].

B-lymphocyte counts, immunoglobulin levels, blood serum antiA and antiB isoagglutinin concentrations and lysozyme activity, and hemolytic activity of the complement were measured in 85 healthy men aged 18 to 42 (mean age 34) smoking 15-25 cigarettes daily for 2-25 years and in a reference group of 49 nonsmokers aged 17 to 50 (mean age 31). Tobacco smoking was found to have no effect on the peripheral blood B lymphocyte count, nor on the blood serum concentrations of group isoagglutinins. In men smoking for 6.5 years on an average the absolute count of lymphocytes was elevated vs. the reference value. In those smoking for 18.5 years on an average IgA, IgG, and lysozyme concentrations were lowered. These results evidence that the mechanism of humoral immunity weakening in tobacco smokers is intricate and related to a deficit of many proteins responsible for immunobiological processes in human body.

Adolescent↗
PubMed1989

[Cellular immunity in cigarette smokers].

T-lymphocyte counts have been measured and the skin test with amnestic antigens performed in 85 clinically healthy men aged 18-42 (the mean age 34) smoking 15-25 cigarettes daily during 2-25 years and in a reference group of 49 non-smokers aged 17-50 (the mean age 31). The absolute count of circulating lymphocytes has been found increased in 38 subjects who smoked for up to 10 years (the mean period 6.5 years), whereas in the subjects who smoked for more than 10 years (the mean period 18.5 years) the absolute and the relative counts of T-lymphocytes have been decreased, the tuberculin test has been much more often negative (14.9% vs. 6.1 and 5.3%), as well as the distreptase test (19.1% vs. 8.2 and 5.3%). These data confirm the suppressor effect of tobacco smoke, inhaled for a long time, on cell-mediated immunity in humans.

Adolescent↗