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Biomedical subjects

P Moulaert

Publications and source records attributed to P Moulaert.

8 recordsLinked to original sources
PubMed1989

Treatment of acute nonspecific delirium with i.v. haloperidol in surgical intensive care patients.

Acute delirium may be treated by the alleviation of pain, by the restoration of specific physiological equilibria (by means of oxygen, glucose, vitamins, etc.) or by discontinuing psychotogenic medication. Acute nonspecific delirium can be treated with a specific psychopharmacological agent. Six surgical intensive care patients with acute nonspecific delirium were treated effectively with intravenous haloperidol. A dose of 38 +/- 17 (mean +/- SEM) mg was needed to calm them. Respiratory rate, heart rate and systolic-diastolic arterial blood pressure all significantly decreased returning to normal values. No side effects were recorded.

Acute Disease↗
PubMed1988

Comparison of evoked electromyography and mechanical activity during vecuronium-induced neuromuscular blockade.

The relationship of compound electromyography to mechanical myography was investigated in 20 patients given vecuronium in a dose of 0.1 mg kg-1. Mechanical response was affected less quickly and recovered faster than the electrical response. Although there was a good correlation between the two throughout the study, a shift towards mechanical responses was observed in all cases for the onset of blockade and recovery from blockade. Moreover, during recovery the mechanical responses became greater than the control value in all patients. This was also reflected in the statistically significant difference (P less than 0.05) of the regression lines relating tension and electromyography (TI as well as train-of-four ratio) between onset of, and recovery from, neuromuscular block.

Electromyography↗
PubMed1988

Noncompartmental pharmacokinetic analysis of nondepolarising neuromuscular blocking agents.

Noncompartmental pharmacokinetic methods using the statistical moment theory can be very helpful in comparing the mean residence time of drugs in the body. These methods are based on the estimation of the area under the time versus plasma concentration curve after a single intravenous drug bolus, and can also be used to estimate clearance, effective half life and the apparent volume of distribution of the drug. In the group of nondepolarising neuromuscular blocking drugs, atracurium offers the advantage of having the smallest mean residence time.

Half-Life↗
PubMed1984

Isoflurane anesthesia for resection of pheochromocytoma. A report of two cases.

Isoflurane was selected as the main agent for induction and maintenance of anesthesia in two patients scheduled for resection of pheochromocytoma. The inspired concentration was calculated with a pocket computer (Sharp PC 1401) and adjusted to maintain an alveolar concentration of 1.5 to 1 MAC. With this technique, a stable heart rate was observed, without arrhythmias. The blood pressure stabilised at normal levels before surgery and only moderate hypertension was seen during tumor manipulation. No specific antihypertensive medication was needed. Transient hypotension after tumor resection was treated with ephedrine and volume replacement. Recovery of anesthesia was rapid and uneventful.

Adrenal Gland Neoplasms↗
PubMed1980

Identification of the causative antigen in immune complex allergy. A simple method.

Two cases are presented of an anaphylactoid reaction after intravenous drug injection. The first reaction immediately after the operation, the second during the induction. At the first sight it was not clear which substance was responsible. Therefore a technique was developed in cooperation with the Immunologic laboratory in order to diagnose exactly the causative antigen. This method is described.

Antigens↗