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Biomedical subjects

P Moullot

Publications and source records attributed to P Moullot.

18 recordsLinked to original sources
PubMed1989

[Probable side effects caused by plethoryl. Common acute hepatitis, anicteric hepatitis, cirrhosis due to hypervitaminosis A, inflammatory arthralgias].

Plethoryl is a combination of triatricol, cyclovalone and vitamin A normally prescribed in the treatment of hypercholesterolaemia. Four cases of side-effects most probably caused by this product are reported. They include: 1) a case of common acute hepatitis, 23 cases of which have already been published, with aggravation and reduced time-lapse after reintroduction; 2) a case of clinically silent but biochemically classical hepatitis; 3) a case of cirrhosis due to vitamin A toxicity; 4) a case of inflammatory arthralgias recurring after the same time-lag when the drug was reintroduced despite double doses and without clinical evidence of hepatitis. The last three side-effects have never been previously reported. The adverse reactions to Plethoryl almost always occur in the unofficial indications of the product, notably in the "treatment" of obesity.

Acute Disease↗
PubMed1987

[Apparently superficial epidermoid cancer of the esophagus: value of radiotherapy and electrocoagulation].

A 77 years old man has been treated by roentgenotherapy for an epidermoid carcinoma of the esophagus. The lesion extended from 24 to 37 cm of the arcades and did not modify roentgenographically the contraction of the muscular layer. This cancer has been heralded by inhalations when swallowing. An error of focusing of radiotherapy resulted in an under irradiation of the upper segment of the esophagus. At the same level a recurrency of the lesions has been treated by electrocoagulation under fibroscopy. The palliation was good but it did not prevent multiple recurrences. The remainder of the esophagus which received 60 Grays has been cured during the three years of follow-up. A second patient has a asymptomatic microcarcinoma at 32 cm. seemingly superficial and was cured by 60 Grays after a follow-up of seven years. External roentgenotherapy is compared to surgery and the use of local treatments as electrocoagulation, laser therapy and intraluminal roentgentherapy are discussed.

Aged↗
PubMed1985

[Treatment of acute colectasia not due to cryptogenic colitis. 4 cases].

Four patients with acute colonic pseudo-obstruction were treated by colonoscopic aspiration. This treatment proved sufficient in 1 case due to Salmonella colitis and 1 case of parkinsonian dysautonomia. It has made it possible to diagnose a pyocholecyst masked by the colonic dilatation it had provoked, and facilitated its surgical treatment. A transient result was obtained in a case of otherwise asymptomatic choleperitoneum. Colonoscopy was relatively easy, perfectly well tolerated and always useful. It is therefore recommended for the treatment of acute colonic pseudo-obstruction except in cryptogenic colitis where its effectiveness and safety have not been demonstrated.

Acute Disease↗
PubMedDate not supplied

[Acute pancreatitis complicating biliary distomatosis caused by Fasciola hepatica in a patient with a choledochal diverticulum].

A 43 years old man presented with acute pancreatitis following 13 years of mild grade hepatic colitis and angiocholitis. The absence of visible gall stone evocated the possibility of millithiasis. The operation discovered a big and hard head of the pancreas and an hypertrophied choledocal mucous membrane and the microscopic analysis of bladder's bile, ova of Fasciola hepatica. A control opacification on the 7th day revealed an adult fluke and a small diverticulum which were not visible on the roentgenogram at the time of the operation. Seven infusions of 60 mg de dehydroemetin permitted to eliminate the fluke with only a peak of fever. The diagnostic, pathophysiologic and therapeutic implications are discussed.

Acute Disease↗