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Biomedical subjects

P Oldenkott

Publications and source records attributed to P Oldenkott.

At least 19 recordsLinked to original sources
PubMed1992

Postoperative spondylodiscitis: results of a prospective study about the aetiology of spondylodiscitis after operation for lumbar disc herniation.

In 412 patients undergoing surgery for herniated lumbar discs from September 1986 to September 1987 and from January 1988 to July 1989 a microbiological specimen was taken from the intervertebral disc space and from the cover of the operating microscope. Also the tips of the wound drains were examined microbiologically after removal. 17% of the patients had a positive bacteriological culture from their intervertebral disc space; 12% of the specimen from the operating microscope were positive. These results favour the hypothesis that intra-operative contamination of the disc space, in contrast to haematogenous spread, causes spondylodiscitis. On the other hand we saw during this time course only one case of clinical spondylodiscitis, which implies a possible involvement of other predisposing factors such as pre- or perioperative infections or compromised patient immunologically. It is also possible, that the routine application of local antibiotic or antiseptic solutions into the disc space at the end of the operation could decontaminate the operative site and prevent clinical infection despite positive culture findings.

Adolescent↗
PubMed1989

[Subarachnoid hemorrhage and intracerebral hematoma in injury of the middle meningeal artery (aneurysma spurium)].

Traumatic lesions of meningeal arteries represent the typical cause of the acute epidural hematoma. Under certain circumstances, however, they may be the origin of space-occupying hemorrhages with only an intradural extent, e.g. subdural or intracerebral hematomas. We present a case of a temporal lobe hematoma with an additional subarachnoid hemorrhage. This gave rise to the suspicion of a spontaneously ruptured cerebral aneurysm that might have caused the patient's accident. Preceding the evacuation of the hematoma, cerebral angiography ruled out the suspected vascular malformation, but revealed a pseudoaneurysm of the middle meningeal artery close to a skull fracture. Intraoperatively, this lesion proved to be the source of the bleeding which was exclusively directed towards the intradural space. Presented is a review of the relevant literature regarding atypical hematomas secondary to meningeal artery lesions and traumatic aneurysms of these vessels.

Adult↗
PubMed1988

Lumbar intervertebral disk herniation with a concomitant nerve root neurinoma at the same site. Case report and review of the literature.

The coincidence of a lumbar disk herniation L4-5 and a neurinoma at the L5 nerve root in a 52-year-old male is reported. The clinical course revealed typical signs of a herniated disk, whereas the tumour was accidentally found by myelography initially performed for the suspected prolapse. Both lesions were removed without complications. The clinical and neuroradiologic aspects of this rare condition are discussed, with special regard to the problems of differential diagnosis. A review of the literature is added.

Humans↗
PubMed1982

[Unusual radiological and clinical findings in a calcified chronic extradural haematoma (author's transl)].

In three of 32 patients with epidural haematomas calcifications and ossifications of the bleeding were found. Quickly developing (3 to 7 weeks) ossifications could be demonstrated by repeated X-rays and CT of the skull in partial drained or untreated haematomas. No ossification could be observed in the remaining 29 cases, in which the haematomas were completely removed. The growth of the ossification from the parietal to the visceral side within the capsules of the haematomas could be monitored in its progress by CT and was histologically verified. The underlying pathological mechanisms are discussed.

Adult↗
PubMed1981

Rupture of an intracranial aneurysm of the carotid artery with ventricular visualization during angiography.

Rupture of an aneurysm during angiography, with extravasation of blood and contrast medium into the ventricular system occurs rarely. We wish to add one personal observation to those few cases already published. Haemorrhage from an aneurysm of the internal carotid artery recurred during angiography in a 52-year-old comatose man. Through extravasation of blood and contrast medium into the ventricles these became fully visible on the X-ray screen. The question of a direct causal relationship between angiography and rupture of an aneurysm, the frequency and risk of this coincidence and mortality are discussed. Since computerised tomography now precedes angiography in cases of subarachnoid haemorrhage, complications arising from angiography could be reduced by proper timing.

Carotid Artery Diseases↗
PubMed1976

[Changes in 2,3-diphosphoglycerate Levels in Blood and Brain Tissue after Craniocerebral Trauma and Cardiac Surgery].

The response of the 2,3-diphosphoglycerate (DPG) levels in the blood and brain tissue to a craniocerebral trauma of varying severity was studied in anaesthetized rats. A trauma producing cerebral contusion was followed within two hours by a highly significant rise in DPG concentration in the blood as compared with the control animals or only mildly traumatized rats. The DPG levels in the brain tissue showed no significant differences. Similar changes in DPG concentration were observed in the blood of patients with craniocerebral injuries. The DPG-mediated increased release of oxygen to the tissues represents a compensatory mechanism and is pathognomic for craniocerebral trauma. Patients undergoing surgery with extracorporeal circulation lack this mechanism for counteracting hypoxaemia; already during thoracotomy the DPG concentration in the blood fell significantly and did not reach its original level until 72 hours after the operation. In stored, ACD stabilized, blood the DPG concentration gradually decreases. Estimations carried out over 28 days showed a continuous statistically significant loss of DPG. After 24 hours the DPG levels in stored blood had already dropped to the lower limits of normal - a fact that has to be taken into account in massive blood transfusions.

Adult↗