Biomedical subjects

P P Freitas

Publications and source records attributed to P P Freitas.

5 recordsLinked to original sources

PubMed2003

Determination of the composition of light thin films with artificial neural network analysis of Rutherford backscattering experiments.

AlO(x)N(y) ultrathin films are used as insulating layers in advanced microelectronic devices. Structural characterization of these films is often done by the Rutherford backscattering (RBS) analysis. The RBS analysis of these oxinitrides is a difficult task since the relevant signals of the spectrum are washed out by the large substrate background and a considerable time is required for an analyst to characterize the sample. In this work we developed specialized artificial neural networks that are able to perform a fast and efficient analysis of the data. The results are in good agreement with traditional methods.

Journal Article↗

PubMed2003

Quasiballistic magnetization reversal.

We demonstrate a quasiballistic switching of the magnetization in a microscopic magnetoresistive memory cell. By means of time resolved magnetotransport, we follow the large angle precession of the free layer magnetization of a spin valve cell upon application of transverse magnetic field pulses. Stopping the field pulse after a 180 degrees precession rotation leads to magnetization reversal with reversal times as short as 165 ps. This switching mode represents the fundamental ultrafast limit of field induced magnetization reversal.

Journal Article↗

PubMed2003

Phase coherent precessional magnetization reversal in microscopic spin valve elements.

We evidence multiple coherent precessional magnetization reversal in microscopic spin valves. Stable, reversible, and highly efficient magnetization switching is triggered by transverse field pulses as short as 140 ps with energies down to 15 pJ. At high fields a phase coherent reversal is found revealing periodic transitions from switching to nonswitching under variation of pulse parameters. At the low field limit the existence of a relaxation dominated regime is established allowing switching by pulse amplitudes below the quasistatic switching threshold.

Journal Article↗

PubMed2003

High sensitivity detection of molecular recognition using magnetically labelled biomolecules and magnetoresistive sensors.

Small magnetoresistive spin valve sensors (2 x 6 microm(2)) were used to detect the binding of single streptavidin functionalized 2 microm magnetic microspheres to a biotinylated sensor surface. The sensor signals, using 8 mA sense current, were in the order of 150-400 microV for a single microsphere depending on sensor sensitivity and the thickness of the passivation layer over the sensor surface. Sensor saturation signals were 1-2 mV representing an estimated 6-20 microspheres, with a noise level of approximately 10 microV. The detection of biomolecular recognition for the streptavidin-biotin model was shown using both single and differential sensor architectures. The signal data compares favourably with previously reported signals for high numbers of magnetic microspheres detected using larger multilayered giant magnetoresistance sensors. A wide range of applications is foreseen for this system in the development of biochips, high sensitivity biosensors and the detection of single molecules and single molecule interactions.

Antigen-Antibody Complex↗

PubMed2002

Domain wall relaxation, creep, sliding, and switching in superferromagnetic discontinuous Co(80)Fe(20)/Al(2)O3 multilayers.

The ac susceptibility of a superferromagnetic discontinuous multilayer [Co(80)Fe20(1.4 nm)/Al(2)O3(3 nm)](10) is measured as a function of temperature, frequency, and field amplitude and compared to static and dynamic hysteresis loops. Its properties are successfully mapped onto the predicted [T. Nattermann, V. Pokrovsky, and V. M. Vinokur, Phys. Rev. Lett. 87, 197005 (2001)]] dynamical phase transitions, which link the relaxation, creep, sliding, and switching regimes of pinned domain walls.

Journal Article↗