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Biomedical subjects

P P Kanjilal

Publications and source records attributed to P P Kanjilal.

5 recordsLinked to original sources

Analysis and characterization of photo-plethysmographic signal.

Qualitative assessment of the overall clinical status of the subject and characterization of complex cardiovascular dynamics from digital blood volume pulsations measured noninvasively using a photo-plethysmographic device is addressed. A novel concept is employed to detect the dominant nonsinusoidal periodicity embedded in the data series and to extract the associated periodic component. The detection and the extraction of periodic component is performed with moving window to accommodate the variations of the physiological oscillations. The covariance matrix formed by the gradually varying pattern is used as a simple measure of qualitative assessment. Further, the characterization of the underlying system in the light of nonlinear dynamical analysis is also presented. The stable subjects are shown to behave as a low-dimensional system whereas the diseased subjects exhibit comparatively high dimensional activity.

Adult↗

Decomposition of posterior alpha rhythm.

The classical posterior alpha rhythm has been decomposed into regular and irregular components using orthogonal transformation. A periodicity generator is considered, which has three characteristic control parameters: the periodicity, the amplitudes or scaling factors and the pattern associated with successive periodic segments. The regular component is shown to be equivalent to an oscillator or periodicity generator whose parameters are dynamically varying and, thus, producing both amplitude- and frequency-modulation. The irregular component is devoid of such modulating behavior. Electroencephalogram signals from normal, maniac and epileptic subjects are studied. Through analytic signal-based analysis, it is shown that for the regular component, healthy brain possesses universal scaling behavior, whereas heterogeneous scaling or absence of universality is observed for the diseased brain.

Adolescent↗

Revisited measles and chickenpox dynamics through orthogonal transformation.

The question addressed is whether or not childhood epidemics such as measles and chickenpox are characterized by low-dimensional chaos. We propose a new method for the detection and extraction of hidden periodic components embedded in an irregular cyclical series, and study the characterization of the epidemiological series in terms of the characteristic features or periodicity attributes of the extracted components. It is shown that the measles series possesses two periodic components each having a period of one year. Both the periodic components have time-varying pattern, and the process is nonlinear and deterministic; there is no evidence of strong chaoticity in the measles dynamics. The chickenpox series has one seasonal component with stable pattern, and the process is deterministic but linear, and hence non-chaotic. We also propose surrogate generators based on null hypotheses relating to the variability of the periodicity attributes to analyse the dynamics in the epidemic series. The process dynamics is also studied using seasonally forced SEIR epidemic model, and the characterization performance of the proposed schemes is assessed.

Chickenpox↗

Fetal ECG extraction from single-channel maternal ECG using singular value decomposition.

The extraction of fetal electrocardiogram (ECG) from the composite maternal ECG signal obtained from the abdominal lead is discussed. The proposed method employs singular value decomposition (SVD) and analysis based on the singular value ratio (SVR) spectrum. The maternal ECG (M-ECG) and the fetal ECG (F-ECG) components are identified in terms of the SV-decomposed modes of the appropriately configured data matrices, and elimination of the M-ECG and determination of F-ECG are achieved through selective separation of the SV-decomposed components. The unique feature of the method is that only one composite maternal ECG signal is required to determine the F-ECG component. The method is numerically robust and computationally efficient.

Artifacts↗

Continuous non-invasive beat-by-beat blood pressure (B.P.) measurement in the newborn.

Intermittent measurement of blood pressure (BP) is frequently performed in newborn babies under intensive care using an inflatable cuff encircling either the arm or leg. This paper describes work aimed at achieving continuous beat-by-beat measurement of the arterial pressure waveform by means of a finger cuff, the pressure of which is controlled by a feedback arrangement utilising a photoplethysmograph. Preliminary results are encouraging, but improvements to cuff design are still needed.

Blood Pressure Determination↗