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Biomedical subjects

P P Vancea

Publications and source records attributed to P P Vancea.

At least 19 recordsLinked to original sources

Lamellar keratoplasty in keratoconus.

The authors present the results of 11 keratoplasties in cases of keratoconus, comparing the visual acuity and the ocular refraction before and after the operation (ophtalmometry, objective and subjective refractometry). The statistical data indicate a meaningful flattening of the corneal curvature (12.84 dpt average) and a mean reduction of the myopia for 8.227 dpt. In fact, the basic regular astigmatism of the cornea had not been altered. The mean visual acuity was 0.68 (with an improvement of 0.495). No further damage of acuity had been observed. After 10 to 69 months a medical checkup revealed transparent grafts in five cases; four presented small maculae; one, thin folds of Descemet's membrane. Based on the authors' experience and on the literature, the paper recommends lamellar keratoplasty in cases of keratoconus, the surgeon must choose the appropriate moment in the course of the development of this disease.

Adult

[34 epibulbar malignant tumours (author's transl)].

Based on a study of 34 cases, the authors make therapeutical and diagnostical references concerning the epibulbar malignant tumours. These were met with a frequency of 10% of the total amount of the malignant tumours of the visual apparatus. The most frequent setting were at the level of the bulbar conjunctiva and of the sclero-corneal limb, especially in front of the opening of the palpebral slit and in the temporal area. The histological examination of the tumours pointed out the following morphological types; epitheliomas (61%), especially spino-cellular, malignant melanomas (32%) and sarcomas (6%). The therapeutical attitude was the surgical one -- the accurate extirpation -- in the limited tumours, followed by radiotherapy when neoplasic lesions were found at the limit of section. In the invaded tumours, the exenteration of the orbit was performed followed by radiotherapy. On the terms of such a therapeutical conduct, the distant prognosis proved to be dependent on two factors: a. The early diagnosis, that is the stage of the therapeutical action. It is insisted upon the importance of the signs of malignization of some benign tumors: papillomas or naevi. b. The nature and origin of the tumour: the secondary tumours are more severe from the beginning.

Adolescent

[Diagnostic and therapeutic problems in a clinical case of oculoauricular dysplasia associated with mandibule-facial dysostosis (Franceschetti-Goldenhar syndrome)].

The authors present a case of oculo-auricular dysplasia (type Goldenhar) associated with France-schetti's syndrome (mandibulo-facial dysostosis) and complicated by paralytic strabismus and genital malformations. Complete investigation failed to establish a precise aetiology; one suggests an external disturbance in the course of the organogenesis of the branchial arches. Aesthetic improvement was undertaken--removal of epibulbar dermoids, correction of the squint, and ablation of the preauricular appendages; functional orthodontic treatment continues.

Adult

On the individual pressure tolerance of the glaucomatous eye.

The individual pressure tolerance of any eye can be determined by taking account of the age, the values of the mean arterial pressure APm, the C/D ratio and the degree of deterioration of the visual field. The method developed opens the way to new possibilities in anti-glaucomatous therapy by making it possible to know the value of the maximum pressure (IPT) which can be supported by the eye under treatment. That treatment must succeed in reducing the value Pi to below the value IPT, if it is to be hoped that the evolution of the glaucoma will be stopped.

Blood Pressure

[Considerations of malignant ocular tumours in children (author's transl)].

The authors undertake a clinico-anatomical study of 27 malignant tumours of the orbit and eye in children seen at the Ophthalmological Clinic in Jassy over the last 12 years. The majority (18 cases) were intra-ocular tumours which were clinically and anatomically retinoblastomas. After presenting the clinical symptoms, drawing attention to the signs of the disease presenting to paediatricians, the treatment is described. This was surgical in all cases followed by radiotherapy according to the case. Analysis of fatal cases and those which survived demonstrate certain degrees of seriousness in clinical, histopathological and therapeutic aspects. It can be appreciated that the long-term prognosis of these cases depends on the early diagnosis and the institution of the correct treatment as well as the anatomopathological form.

Adolescent