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Biomedical subjects

P Parmananda

Publications and source records attributed to P Parmananda.

18 recordsLinked to original sources

Fingerprints of determinism in an apparently stochastic corrosion process.

We detect hints of determinism in an apparently stochastic corrosion problem. This experimental system has industrial relevance as it mimics the corrosion processes of pipelines transporting water, hydrocarbons, or other fuels to remote destinations. We subject this autonomous system to external periodic perturbations. Keeping the amplitude of the superimposed perturbations constant and varying the frequency, the system's response is analyzed. It reveals the presence of an optimal forcing frequency for which maximal response is achieved. These results are consistent with those for a deterministic system and indicate a classical resonance between the forcing signal and the autonomous dynamics. Numerical studies using a generic corrosion model are carried out to complement the experimental findings.

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Tracking fixed-point dynamics in an electrochemical system using delayed-feedback control.

We report numerical and experimental results indicating successful tracking of stabilized fixed points solutions in an electrochemical system. By applying a continuous delayed-feedback technique, periodic oscillations are suppressed via stabilization of a steady-state fixed point. Subsequently, using a simple continuation method involving an update term, this stabilized fixed point is tracked through the bifurcation diagram as a system parameter is slowly varied. Under the influence of this tracking protocol, inception of oscillatory dynamics is precluded over large parameter domains and through bifurcations.

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Experiments on coherence resonance: noisy precursors to Hopf bifurcations.

Experimental and numerical evidence of coherence resonance in an electrochemical system is reported. External noise with a Gaussian distribution is superimposed on the system when the anodic current is exhibiting stationary (fixed point) dynamics below a supercritical Hopf bifurcation. The amplitude of the added stochastic perturbations is increased monotonically and the induced oscillatory behavior is analyzed. It is observed, both in experiments and in simulations, that the regularity of the noise induced current oscillations reaches a maximum value for an optimum noise level. This is indicative of coherence resonance and can be explained with a mechanism based on noisy precursors to a Hopf bifurcation.

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Resonant forcing of a silent Hodgkin-Huxley neuron.

Dynamical behavior of a silent Hodgkin-Huxley neuron subjected to external periodic perturbations is investigated. Induced dynamics for this forced system, exhibit nonlinear resonance with respect to the forcing frequency. Within the U-shaped resonance curve, both regular (phase locked) and irregular spike sequences are invoked. For appropriate tuning frequencies, this simple system generates spike trains recordings similar to ones observed in actual experiments.

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Resonances via deterministic and stochastic perturbations: a comparative study.

We study periodic and coherence resonances invoked by aperiodic yet deterministic perturbations. Chaotic perturbations with varying levels of intrinsic correlations are superimposed parametrically on an excitable chemical model. This enables us to analyze the system response and characterize the induced resonances as a function of correlation in the perturbing signal. Using standard measures such as normalized variance and normalized number of peaks, dynamics for different deterministic signals are quantified and eventually compared to resonances invoked via stochastic perturbations.

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Suppressing spatiotemporal disorder via local perturbations in an electrochemical cell.

We report experimental results depicting suppression of complex spatiotemporal dynamics under the influence of local periodic stimulations. In an experimental electrochemical system, applying a continuous forcing signal to one of the sites in an array of eight coupled oscillators, the naturally complex behavior of the remaining seven electrodes can be converted to periodic responses. The oscillations remain periodic as long as the forcing is active and revert back to exhibiting chaotic dynamics after the control is switched off. These results can also be interpreted as experimental realization of "phase-synchronization" induced via local driving in an extended system. A possible relevance to the experimentally observed calcium wave patterns is pointed out.

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Birhythmicity induced by perturbing an oscillating electrochemical system.

We describe the generation of new limit cycles in electrochemical systems under the influence of external periodic perturbations. For certain specific parameters of a nonharmonic forcing function, two coexisting periodic orbits can be generated from a single limit cycle observed in the unperturbed dynamics. This inception of birhythmicity (bistability) is observed in both simulations and actual experiments involving potentiostatic electrodissolution of copper in an acetate buffer.

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Maintenance of transient chaos using a neural-network-assisted feedback control.

A stable period-3 orbit in the parametric vicinity of a chaotic attractor is destabilized using two distinct feedback strategies. This results in the inception and subsequent maintenance of the otherwise short-lived chaotic transients. Both the techniques employed are based on the exclusion of trajectories from the near vicinity of the open loop stable period-3 attractor; the first relies on the traditional proportional feedback method while the second one includes a predictive term enabling delimitation of exclusion zones for the system dynamics. The implementation of these strategies involves construction of appropriate reference models in the form of an artificial-neural-network approximator.

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Resonance induced pacemakers: a new class of organizing centers for wave propagation in excitable media.

Propagation of waves in an extended excitable system is considered. It is shown that traveling wave fronts can be triggered and maintained via local periodic modulations of an appropriate system parameter. For a finite range of perturbation frequencies, this new class of pacemakers introduces spatiotemporal self-organization in an otherwise quiescent medium. Excitation waves of activity similar to those observed in heart tissue cultures and other biological preparations can emerge in the presence of these pacemakers.

Biological Clocks↗

Controlling spatiotemporal chemical chaos using delayed feedback.

Control of chemical chaos in a spatially extended system mimicking CO oxidation on a Pt(110) single-crystal surface is achieved using delayed feedback techniques. For appropriate parameter values the uncontrolled model system exhibits both amplitude and phase turbulence. Superimposing a delayed feedback on the natural dynamics, suppression of spatiotemporal complexity is attained via stabilization of ordered states consisting of stable patterns.

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Human electroencephalogram induces transient coherence in excitable spatiotemporal chaos.

A time series from a human electroencephalogram (EEG) is used as a local perturbation to a reaction-diffusion model with spatiotemporal chaos. For certain finite ranges of amplitude and frequency it is observed that the strongly irregular perturbations can induce transient coherence in the chaotic system. This could be interpreted as "on-line" detection of an inherently correlated pattern embedded in the EEG.

Brain↗

Noise-aided control of chaotic dynamics in a logistic map

Controlling chaos involves employing small perturbations to a control parameter, resulting in the stabilization of the system (naturally chaotic) on one of the infinite unstable periodic orbits embedded in the chaotic attractor. In this Brief Report we study the constructive role of external noise in increasing the efficiency of controlling chaos. Using a logistic map as an example, control of chaotic dynamics is achieved using a linear delayed-feedback strategy. Working in the subthreshold regime of control (where the value of control constant is less than the minimum value required to stabilize the period-1 target state), system dynamics in the presence of superimposed noise (system plus control plus noise) exhibit a resonance effect. Furthermore it is observed that the time required to reach the target state decreases appreciably in the presence of an optimum level of noise.

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Self-exciting chaos as a dynamic model for irregular neural spiking

We introduce a nonlinear dynamical system with self-exciting chaotic dynamics. Its interspike interval return map shows a noisy Poisson-like distribution. Spike sequences from different initial conditions are unrelated but possess the same mean frequency. In the presence of noisy perturbations, sequences started from different initial conditions synchronize. The features of the model are compared with experimental results for irregular spike sequences in neurons. Self-exciting chaos offers a mechanism for temporal coding of complex input signals.

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Stabilization of unstable steady states and periodic orbits in an electrochemical system using delayed-feedback control.

We report numerical and experimental results indicating successful stabilization of unstable steady states and periodic orbits in an electrochemical system. Applying a continuous delayed-feedback technique not only periodic and chaotic oscillations are suppressed via stabilization of steady-state solutions but also the chaotic dynamics can be converted to periodic behavior. In all cases the feedback perturbation vanishes as a target state is attained.

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