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Biomedical subjects

P Pavone

Publications and source records attributed to P Pavone.

At least 181 records · Page 10Linked to original sources
PubMed1986

Gold storage in the liver: appearance on CT scans.

The authors present one case in which high attenuation values in the liver parenchyma on computed tomographic scans were found in a patient who had been previously treated with colloidal gold for rheumatoid arthritis. Reticuloendothelial storage of gold was proved by biopsy.

Arthritis, Rheumatoid↗
PubMed1985

Digital celiac arteriography.

Sixty patients underwent intraarterial DSA with injection into the celiac artery for evaluation of various hepatic, pancreatic, and splenic lesions. Twenty of these patients also underwent conventional arteriography for comparison. Excellent images during the early arterial phase (free of bone superimposition and artifacts) were obtained with DSA. The late arterial and parenchymal phases of the examination were less definitive when compared with conventional angiography. The venous phases of the liver studies were good and compared favorably in contrast and resolution to conventional methods. In the late venous phase, good images of the portal system were obtained using a small amount of contrast medium. Respiratory movements and artifacts were overcome with postprocessing. Most of the studies were performed using the 12-inch mode of the image intensifier, which represents the best choice between the size of the field examined and the spatial resolution of the system. We believe that DSA is a suitable substitute for conventional angiography in most patients in whom celiac trunk angiography would be used.

Angiography↗
PubMed1985

CT of functioning tumors of the pancreas.

Thirty-three patients suspected of having a functioning tumor of the pancreas were studied with computed tomography (CT); 25 had angiographic studies also. Thirty-one cases were confirmed surgically; the other two were lost at follow-up and were excluded from the series. Of the 31 patients, 21 had insulinomas, five had Zollinger-Ellison syndrome, and five had assorted apudomas. CT was positive in 71% of the cases and negative in 29%; 22.6% of the studies were false negative and 6.4% were true negative. There were no false positives. Of the 21 patients with insulinomas, only one had false-negative CT and angiographic studies, caused by diffuse microadenomatosis. In one patient, two separate lesions of the pancreas were seen and identified correctly on both CT and angiography. All identified lesions smaller than 2 cm were seen only because of a hyperdensity on the enhanced CT scan. Lesions larger than 2 cm were identified either because their size distorted the pancreatic contour or because of their vascularity. The importance of proper CT technique using fast scanners and repeated bolus injections of contrast medium is stressed.

Aged↗
PubMed1985

Detailed evaluation of angiographic findings in the surgical assessment of resectability for pancreatic cancer.

The role of angiography as a diagnostic approach and surgical assessment of resectability in pancreatic cancer patients is considered. Pre-operative arteriography of the celiac axis and superior mesenteric artery was performed in 27 patients with surgically proved pancreatic cancer. The operatibility of each patient was assessed according to arteriographic findings. The arteriographic features considered to establish tumor unresectability included: neoplastic arterial encasement or displacement, multiple involvement of pancreatic arteries, involvement of portal, splenic or superior mesenteric veins, liver metastasis. Nineteen angiographically predicted unresectable lesions proved to be unresectable at surgery. Of the eight additional patients who showed no remarkable unresectable angiographic features, 6 were confirmed resectable, while 2 were unresectable. Angiography was shown to be very accurate in differentiating resectable from unresectable cancer of the pancreas.

Adenocarcinoma↗
PubMed1983

Digital subtraction angiography for examination of vessels of the leg: use of a 40-cm image intensifier.

Digital subtraction angiography (DSA) using a 41-cm (16-in.) image intensifier was performed in 144 patients with peripheral vascular insufficiency. In most cases the entire peripheral vascular bed from the renal arteries to the popliteal trifurcation was demonstrated with four intravenous injections and four exposed fields: (a) aorto-iliac, (b) ilio-femoral, (c) femoro-popliteal, and (d) popliteo-tibial. In 90% of cases the procedure was diagnostic in all regions studied, while in 10 it was nondiagnostic in one or more regions for various reasons (myocardial insufficiency, inadequate contrast bolus, or technical failure). Most failures involved the distal arteries. In spite of some limitations, intravenous DSA using a large-field image intensifier may replace conventional angiography in routine preoperative evaluation of peripheral vascular disease, with intra-arterial injections being performed when the intravenous technique is nondiagnostic.

Adult↗
PubMed1982

[Clinical evaluation of the therapeutic effect of D-L-carnitine in the acute phase of myocardial infarct in relation to the behavior of the serum myoglobin concentration curve].

Clinical experience carried out on 40 patients with AMI - 22 of them treated with 15 g daily of D-L-Carnitine and 18 untreated - is reported. Our interest was to study the therapeutic action of this drug evaluating if it was able to modify the curve of serum myoglobin level released from necrotic or ischaemic areas. The conclusion is drawn that this drug could act feebly only during the earlier stages of AMI, but many reserves are expressed.

Aged↗