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Biomedical subjects

P Pecora

Publications and source records attributed to P Pecora.

At least 19 recordsLinked to original sources
PubMed1984

[Behavior of vitamin A, beta-carotene, retinol binding protein and prealbumin in the plasma of hypo- and hyperthyroid subjects].

Plasma concentrations of beta-carotene and retinol, determined by HPLC, and of transport proteins, ascertained by immunodiffusion technique, in hypo and hyperthyroid subjects are reported. In hypothyroid subject a considerable increase in carotene was noted. This was not the case for retinol. In hyperthyroids both beta-carotene and retinol levels were found to be normal. Transport protein (PA and RBP) levels were found to be lower only in cases of hyperthyroidism but unchanged for hypothyroids. According to the Authors the results show that the alteration in plasma carotene levels to be found in hypothyroid subjects is not the direct consequence of a lack of thyroid hormone in the metabolism of vitamin A but the indirect effect of thyroid disease.

Adult↗
PubMed1984

[Effect of renal and liver failure on blood levels of vitamin A, its precursor (beta-carotene) and its carrier proteins (prealbumin and retinol binding protein)].

Plasma beta-carotene and retinol assay was performed by high pressure liquid chromatography (HPLC) in subjects with chronic renal failure or liver cirrhosis. In the same subjects blood prealbumin (PA) and retinol binding protein (RBP) were determined by immunological technique. A considerable increase of retinol and in a lesser extent of beta-carotene was noted in the blood of patients with renal insufficiency. In cirrhotic patients it was shown a marked decrease both of beta-carotene and retinol plasma concentrations. PA and RBP there were greatly increased in renal failure and decreased in liver cirrhosis. This results suggest that kidney and liver chronic failure interfere with vitamin A metabolism throughout their action on metabolic processes of synthesis and elimination of PA and RBP.

Carotenoids↗
PubMed1984

[Oral load test with beta-carotene in normal and dysthyroid subjects].

An oral load of beta-carotene (500 mg) was administered to four normal, four hypo and four hyperthyroid subjects. Plasma beta-carotene content was determined at the 2nd, 4th, 6th, 8th, 10th, 12th and 24th hour after administration and at every 24th hour thereafter for 5 consecutive days. Plasma assays were performed by HPLC. No significant differences were revealed by Student's T test for one group to the other. The authors sustain that, as there is no impairment in intestinal uptake of beta-carotene in disthyroid subjects, the elsewhere described increase in carotinemia in hypothyroids is due to other mechanisms.

Carotenoids↗
PubMed1983

[Effect of parturition on serum glycerol and non-esterified fatty acids in obese and normal weight women].

Serum glycerol and NEFA content variations are examined before and after labor in obese and normal weighing women (35 subjects). Blood glycerol and NEFA are shown to increase before delivery. Glycerol values are shown to drop to normal immediately after delivery, while NEFA values diminish to a lesser extent. Statistical analysis shown that blood glycerol increase could be pregnancy-dependent in both normal weighing and obese women, but that NEFA increase could be pregnancy-dependent in normal weighing women only. Obesity increases blood glycerol and NEFA concentration considerably, thus masking the effects of pregnancy.

Fatty Acids, Nonesterified↗
PubMed1983

[Serum content of vitamin A binding proteins (prealbumin and retinol binding proteins) in normal and pathological conditions].

Blood PA and RBP content were estimated in 100 normal subjects (50 men and 50 women). Mean values of 28.2 and 3.75 mg/dl were ascertained for PA and RBP, respectively. The molar ratio RBP/PA was calculated as 0.31 +/- 0.05. Serum concentrations of PA and RBP are seen to be sex-dependent (20% higher in males). Hyperthyroid subjects exhibit a decrease in the two vitamin A-binding proteins whereas no modification could be revealed for hypothyroid states. In patients on maintenance hemodialysis mean serum PA and RBP concentrations were remarkably higher than normal, whereas liver cirrhotic subjects showed a highly significant depression of mean serum RBP and PA values.

Adult↗
PubMed1981

Constipation and obesity: a statistical analysis.

Constipation frequency was investigated among 1897 subjects (874 males and 1023 females), ranging in age from 6 to 70 years, chosen at random between city inhabitants and farmers. Bowel habit was studied in 966 obese patients (390 males and 576 females). The authors followed for the diagnosis of constipation either the commonest and restrictive criterion of the weekly bowel actions or the clinical one which implies also others parameters, like hard or small stools, difficulties of expulsion or feeling of incomplete evacuation after defecation. The statistical analysis showed that constipation frequency is 8.3% in obese patients and 1.5% in normal-weighting, according to weekly bowel actions criterion: the difference is statistically significative (p less than 0.001).

Adolescent↗
PubMed1981

Blood glycerol meaning in obese patients.

The authors studied the behaviour of blood glycerol concentration after glycerol i.v. infusion in obese and normal subjects. The aim of research was to clarify the meaning of blood glycerol increase observed by some one in obese subjects. Results obtained showed that in obese subjects there is not any abnormal behaviour of blood glycerol concentration after infusion and that in none of patients studied was observed any significative increase of basal blood glycerol concentration values.

Adult↗