Biomedical subjects
Publications and source records attributed to P Pera.
The authors, after having considered some structural aspects of the temporomandibular joint, examine the histologic features of the degenerative disease (arthrosis, remodelling, deviation in form).
This article describes a quicker and cheaper method of obtaining an upper jaw impression, and transferring this to the articulator at one sitting.
The article describes a method for obtaining an impression in patients suffering from a loss of maxillo-facial structure with reduced oral aperture. This involves making an individual resin tray, which is then divided in two, with four plugs on the underside for precise re-alignment later. The method suggested facilitates the insertion and removal of the tray. Thus an accurate impression of the perimeter can be obtained without the risk of trauma.
The more common techniques for analysing the alveolar ridge in full dentures were examined. Both the linear analysis and the two-dimensional one, proposed by Pound, were described. The ridge-transfer method was found to be three-dimensional, thus allowing the construction of full dentures which are more stable during each phase of mastication.
The therapeutic effectiveness of EMG biofeedback on muscular relaxation and pain symptomatology has been analysed in a group of 24 dysfunctional patients presenting consecutively at the Prosthesis Department of the Odontostomatological Clinic. A good level of muscular relaxation was achieved in 22 cases; pain symptomatology disappeared totally in 19 and reduced considerably in 3 of 24 patients examined. Therapy failed in 2 cases. The method thus presents unquestionable therapeutic value in dysfunctional patients, particularly in cases with symptomatology that is mainly due to muscular hyperactivity.
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Polyamine biosynthetic activity was assessed in various colorectal tissue samples consisting of noninvolved mucosa, benign adenomatous polyps and adenocarcinomas taken at surgery from a total of 40 patients. Ornithine decarboxylase (ODC) displayed a gradient of enzyme activity (i.e., adenocarcinoma greater than polyps greater than mucosa) which seemed to correlate positively with the neoplastic status of the tissue. In 10 of the patients, samples were obtained for all three tissue types. Five of these exhibited a clear repetition of the trends in enzyme activity seen with the mixed patient tissue sampling whereas the remainder differed by having the highest ODC activity in the polyps. In nine of the ten cases, ODC activity was substantially lower in the mucosa than in either of the neoplastic lesions. Trends in enzyme activity were the same for tissues obtained from either the colon or rectum. The ODC activity in adenocarcinomas could not be correlated with histologic differentiation, stage or site of the disease, however, in samples from female patients (all postmenopausal) the activity was elevated over normal mucosa to a greater extent (ten-fold) than in male patients (seven-fold). S-adenosylmethionine decarboxylase activity was assessed in 27 of the 40 patients and found to follow the same distribution as ODC; however, the mean value differences +/- SEM between tissues were less distinct. In general, tissue polyamine pool analysis of these same specimens reflected the levels of ornithine and S-adenosylmethionine decarboxylase activities. Overall, the data reveal an increase in polyamine biosynthetic activity in colorectal neoplasms, relative to surrounding mucosa, which may correlate with (1) progression of the neoplastic process, (2) the proportion of proliferating cells, (3) the rate of cell proliferation, or (4) a combination of two or all of these possibilities.
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The aims of the study were to examine the morphometric and angular relationships between the interincisive papilla and the maxillary anterior teeth, and to describe a clinical method derived from this analysis useful in sitting the upper front teeth. Plaster casts of upper jaws of adult patients with complete dentition, were selected. Two measurements were taken: the distance from the centre of the papilla to the most vestibular part of the labial surface of the anterior teeth; and the angles between the perpendicular to the median line and the line from the centre of the papilla to the most vestibular part of each tooth. The equation of the resulting parabola, corresponding to the upper frontal arch, can be applied to every maxillary dimension. Parabolas were divided into small, medium, and large, using the mean and standard deviations. Each curve was traced on a transparent base-plate shaped for intra-oral placement. In individuals with complete dentition the closest parabola to the maxillary frontal arch was selected and the distance between the lateral frenula measured. Statistical study demonstrated a correspondence between the interfrenulum distance and the parabolas. In edentulous patients the interfrenulum distance thus provides a curve useful in sitting the maxillary anterior arch.
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