Benefits of ADA membership.
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Biomedical subjects
Publications and source records attributed to P Perich.
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Active rosette forming T lymphocytes (ARTL) represent a subpopulation of T cells with high affinity for sheep erythrocytes. It has been postulated that ARTL reflect the cellular immune status in the human, and in earlier papers we have hypothesized their suppressor activity. In this work ARTL were determined by the method of Wybran. We studied 58 insulin dependent diabetics (IDD), 30 non-insulin dependent diabetics (NIDD) with HbA1c below 8%, and 41 NIDD with HbA1c higher than 8% at the moment of taking the sample. Healthy blood donors were used as controls. We observed a significant decrease of ARTL in IDD at the onset of the disease Normal values were restored from the third month after manifestation ARTL were normal in both groups of NIDD. These findings suggest that insulin may exert an influence on ARTL.
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From 1954, Trypanosoma rhodesiense trypanosomiasis affects North East Burundi in an endemic way. However, for two years (1979-1980) in spite of a constant monitoring, no new trypanosomiasic patient has been detected. The author, in order to appreciate the epidemiological prospects, reviews the history of trypanosomiasis in Burundi and considers the role of the geographical environment, the socio-economic changes and the various attempts to control the disease. Nowadays the existence of animal reservoirs is not proved and the human reservoir seems almost in existant. The vector still exists and the main danger might come from the Tanzanian foci.