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Biomedical subjects

P Piascik

Publications and source records attributed to P Piascik.

At least 19 recordsLinked to original sources
PubMed1998

Biotechnology: an overview of the tools, therapeutic agents, and applications to pharmacy practice.

The promise of pharmaceutical biotechnology and its applications to health care is now being realized. Over 30 therapeutic agents produced by the tools of biotechnology are now available and nearly 300 more are in various stages of development. Recombinant proteins, monoclonal antibodies, gene therapy, and vaccines can provide effective treatments and cures for diseases we could only mitigate in the past. The availability of these drugs presents several interesting challenges and opportunities to pharmacists. The expense, complexity, and unique properties of biotechnology agents will continue to alter not only the knowledge base of pharmacy but also the way pharmacists perform their professional responsibilities.

Antibodies, Monoclonal↗
PubMed1995

Expanding indications for biotechnology agents.

Many biotechnology products currently on the market were initially approved for indications affecting only a small number of patients. However, pharmaceutical manufacturers have continued to study these agents for potential new therapeutic uses. The result is that several of these products are now approved for multiple uses involving large patient populations. In many cases, the biotechnology agents are being used in patients for whom no effective therapy was previously available.

Biotechnology↗
PubMedDate not supplied

Medicinal leeches: ancient therapy is a source of biotech drugs.

Hirudin analogs have been shown to be inhibitors of thrombin with many potential uses. These agents appear to have advantages over conventional anticoagulant agents such as heparin. The hirudin compounds do not require a cofactor to work, have consistent dose-dependent effects, act directly on thrombin, are highly specific, and have little to no toxicity.

Animals↗