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Biomedical subjects

P Piesiak

Publications and source records attributed to P Piesiak.

3 recordsLinked to original sources

[Pulmonary alveolar microlithiasis in a patient with urolithiasis and cholelithiasis].

49 years old woman was admitted to Pulmonary Ward because of respiratory and cardiac failure. Six years earlier she was surgically treated because of urolithiasis and at this time disseminated lesions in both lungs were revealed. Biopsy made during transbronchial procedure showed microlithiasis. She had'nt any respiratory symptoms during 6 years. Now she had PaO2 = 36 mmHg and massive infiltrations in whole lungs. Palliative therapy with diuresis, cardiac drugs and oxygen therapy diminished symptoms of respiratory and cardiac failure.

Biopsy↗

[Rhythm of melatonin excretion in obstructive sleep apnea syndrome].

UNLABELLED: Melatonin is a pineal hormone that regulates sleep and wake status. Melatonin concentrations in blood serum were measured using radioisotope method in 33 males (age 48 +/- 10) with obstructive sleep apnea syndrome. The following melatonin concentrations were measured: 54 +/- 72 pg/ml (9 p.m.) 424 +/- 838 pg/ml (2 a.m.) and 307 +/- 534 pg/ml (6 a.m.). In patients with high peak melatonin concentration (> 200 pg/ml) as compared with the patients with low peak melatonin concentration (< 200 pg/ml) there were higher index of respiratory disorders during sleep (53 +/- 18 vs 38 +/- 20, p < 0.05) and lower minimal SaO2 during sleep apnea (52 +/- 17% vs 70 +/- 10%, p < 0.05); they were also more tired in the morning and were more sleepy during the day (Epworth sleepiness scale 17 +/- 6 vs 11 +/- 6, p < 0.01). In 66% of patients peak melatonin concentration was observed at 2 a.m. In 24% of patients peak melatonin secretion was prolonged to early morning hours. CONCLUSIONS: In most of patients there is peak melatonin excretion at 2 a.m. Patients with high apnea and hypopnea index and daytime sleepiness have high peak melatonin concentrations.

Adult↗

[Lipoid pneumonia].

The authors describe in the article etiology, histopathological features, clinical picture and diagnostics of endogenous and exogenous lipoid pneumonia. The advantages of broncho-alveolar fluid examination and computed tomography in the diagnostics were emphasized.

Bronchoalveolar Lavage Fluid↗