PubMed Health⌕ Search

Biomedical subjects

P Pitche

Publications and source records attributed to P Pitche.

At least 37 records · Page 2Linked to original sources

[Recurrent varicella and HIV infection. Apropos of 10 cases seen in Lomé].

Herpes-zoster is commonly observed in immunodepressed patients with HIV infection in Africa. It is due to reactivation of the varicella-zoster virus. Varicella which is usually considered as the acute invasive phase of infection can recur in the same subject during immunodepression, thus constituting recurrent varicella. Little information is available concerning recurrent varicella in Africa. The purpose of the present report is to describe 10 cases observed in 9 adults and 1 child in Lomé, Togo. In 6 cases recurrence of varicella allowed diagnosis of HIV infection. Clinical symptoms were severe with widespread lesions and fever-related changes in general status. Nine of the 10 patients required hospitalization. In all cases the illness lasted more than 3 weeks. This series demonstrates that varicella in adults can be the first clinical manifestation of HIV infection in tropical areas and that this possibility should be investigated especially if varicella is recurrent.

AIDS-Related Opportunistic Infections↗

[Bullous toxidermatosis and HIV infection in hospital environment in Lome (Togo)].

A transversal study allowed to analyse the different features of severe bullous toxicodermatosis, and its relations with HIV infection. Since March 1992 to December 1995, 15 patients were hospitalized in Lome Teaching Hospital for severe bullous toxicodermatosis: 16 cases of Lyell's syndrome, 8 cases of Stevens-Johnson's syndrome and 1 case of ectodermosis. The principal drug which induced these diseases were mostly dominated by the sulfanilamide (n = 7). Nine (9) of these subjects were infected by the HIV (four of whose patients had Lyell's syndrome). Its noted five cases of death, all in the patients with HIV infection.

Adult↗

[Erysipelas of the leg in hospital environment in Lome (Togo)].

A study was conducted during 5 years to determine the epidemiological clinical profile and the evolution of legs erysipelas in patients attending Lome teaching hospital. During this period, 60 subjects (43 females et 17 males) were hospitalized for legs erysipelas. The average age was 40 years old. General facilitating factors were noted in 58% of the patients (n = 35), and local in 50% of cases (n = 30). The first line treatment was in all patients penicillin G. Satisfactory results were observed in 70%. Local complications were noted in 10% (n = 6), and recurrence in 17% (n = 10). The erysipela is common in hospital environment. The precocious penicillinotherapy allowed to have satisfactory results.

Adult↗

[Cutaneous cancers in Togo].

A retrospective study was conducted during 20 years to determine the epidemiological features of skin cancer diagnosed in the pathology laboratory in Lome teaching hospital. During this period, 518 cases of theses affections were noted: 288 cases of carcinoma (56.6%); out of 288 carcinomas 254 were spinocellular carcinoma, which developed on 143 chronic phagedenic ulcer, the others cancer were: malignant melanoma 63 cases (12.3%), Kaposi's sarcoma 72 cases (13.9%), skin sarcoma 95 cases (18.3%). The results of this study shows that the spinocellular carcinoma were mostly the skin cancer in Black African, and confirm the particularity of malignant melanoma in Black subjects.

Adult↗

[Melanoma in Togo. A retrospective study over 20 years].

INTRODUCTION: The malignant melanoma is a rare malignant tumour in black patients, but it is common in white patients. MATERIAL AND METHODS: Medical records were reviewed retrospectively during 20 years (1973-1992) to determine the epidemiological features of malignant melanoma in Togo. RESULTS: During this period 63 cases (31 males and 32 females) of malignant melanoma were histologically diagnosed; an average of 3.15 cases each year. The tumor takes place preferably on the feet 40 cases (63.49%), hands 15 cases (19.04%), legs and thigh 10 cases (15.87%). CONCLUSION: The results of this study confirm the particularity of malignant melanoma in black subjects: its rarity and the feet localizations.

Adolescent↗

[Venereal vegetations of the urogenital tract and their urological complications. Apropos of 257 cases].

A retrospective study was conducted during 8 years to determine the epidemiological features of condyloma and its complications in patients attending urology consultations in Lomé teaching hospital. During this period, 257 cases (218 males, 38 females) of condyloma were diagnosed. The condyloma represented the fifth cause of consultation in urology, after genito-urinary infection (n = 1214), prostatic dysuria (n = 1095), vesicovaginal fistula (n = 849), lower tractus urinary lithiasis (n = 500). The average age of the patients was 28 years (range: 14-57). In 51 cases the condyloma were associated with others sexually transmitted diseases: 25 cases of gonococcal infection, 11 cases of chancroid, 9 cases of vaginal candidiasis, and 6 cases of genital trichomoniasis. We noted 41 cases of urological complications: 19 cases of urinary infection, 13 cases of retention of urine, 7 cases of urinary forked jet, and 2 cases of urethrorrhagia. The results of this study shows that, the condyloma is commun sexually transmitted disease seen in urology clinic. Its classically benign course in patients males, were predominant, in this sex, by the urinary infection and urological mechanical accidents.

Adolescent↗

[Kaposi's sarcoma in dermatology consultations at Lome, Togo].

The purpose of this retrospective study conducted in a dermatologic out patient clinic in Lomé was to assess the epidemiologic, clinical, and prognostic profile of Kaposi's sarcoma in Togo during the 15 years period between 1980 and 1994. Only patients who had undergone serologic tests for human immunodeficiency virus (HIV) were included. There were 30 patients (27 men and 3 women) with a mean age of 35.2 years (range: 17 to 59 years). Thirteen patients were seropositive (epidemic Kaposi's sarcoma or EPK) and 17 were seronegative (endemic Kaposi's sarcoma or ENK). The mean age of patients with EPK was lower than that of patients with ENK (30.0 vs 42.3 years). Extensive (92.3%) and edematous (90%) forms and involvement of the upper extremities (66.7%), trunk (01.6%), and mucosa (92.3%) were characteristic clinical features of EPK while localized nodular forms (92.3%) were characteristic of ENK. A death was noted after 5 years of follow-up in the ENK group as compared to 12 deaths after a mean follow-up of 15.95 years in the EPK group. This study illustrates the current profile of Kaposi's sarcoma in Black Africa where HIV infection has greatly changed clinical findings and prognosis.

Adolescent↗

[Multiple bone lesions of a type of disseminated African histoplasmosis in a Togolese immunocompetent child].

The authors report one case of disseminated African's histoplasmosis with numerous bones in Togolese immunocompetent child. The left tibia and fibula, the collarbones and the acromion were the bones mostly affected. The chronic fistulate lesion of the left leg associated with skin lesion allowed to evoke the diagnosis, this being confirmed by histological examination. The authors review the different diagnosis which will be discussed considering the radiographic appearance of african's histoplasmosis.

Acromion↗

[Extensive Kaposi's disease with fatal outcome in a young togolese with negative HIV serology].

This is a rare case of extensive multifocal type of Kaposi's disease which developed in a young child. The patient's age, the major and progressive weight loss, the appearance of adenopathies and of a suspected tuberculous pleuritis, the evolution of cutaneous lesions extension, followed by death in short time (5 years) led us to suspect an eventual association with HIV infection. Serologic tests performed three times which remained negative and the absence of other important AIDS signs excluded this diagnostic.

Adult↗

[Persistent pigmented plaques in adult-onset Still's disease].

INTRODUCTION: Adult-onset Still's disease (AOSD) is a systemic affection characterized by intermittent fever, evanescent rash, polyarthralgia or arthritis and neutrophilic leucokytosis. We report a new case of AOSD with persistent pigmented plaques in a Vietnamese woman. CASE REPORT: A 23 year-old woman had presented within several months: inflammatory polyarthralgia, intermittent fever, asthenia, myalgia, weigh loss, polyadenopathy and an evanescent cutaneous rash. In addition, she presented pigmented skin plaques on the trunk. The investigations noted: neutrophilia (10000/mm3) and a high level of serum ferritin (42,000 microg/l). The erythrocyte sedimentation rate was 55mm in the first hour. C reactive protein was normal. HIV and syphilis serologies, antinuclear antibodies and rheumatoid factor were negative. No growth of micro-organisms was observed in repeated blood and urine cultures. The histology of the persistent plaque and lymph node were not specific. It required a high dose of corticosteroid to obtain remission. DISCUSSION: The existence of persistent plaques in AOSD is uncommon. Nevertheless, the exact relationship between the fixed cutaneous lesions and AOSD remains unclear. But their synchronous evolution with systemic symptoms and response to therapy suggest that they represent a specific manifestation of the disease.

Adrenal Cortex Hormones↗

[Etiology of isolated pruritus in dermatology consultations at Lome (Togo)].

A prospective study was conducted to determine the etiologies of isolated pruritus among out-patients attending a hospital dermatology clinic in Lome. Two hundred and twenty patients (120 men and 100 women) suffering from isolated pruritus were included in the study. The most frequent etiologies were; digestive parasitosis (n = 50), onchocercosis (n = 45), drug allergy (n = 26), food allergy (n = 10), psychological pruritus (n = 25) and hepatitis (n = 13). The etiology was not determined for 29 cases. This study shows the large contribution of parasites to the pathogenesis of pruritus in tropical Africa.

Adolescent↗

[Prevalence of skin manifestations in AIDS patients in the Lome-Tokoin University Hospital (Togo)].

A prospective study was conducted for 13 months to determine the prevalence of skin disease in AIDS patients in the Lome teaching hospital. 99 of the 120 AIDS patients (75 males, 49 females) examined during this period had skin diseases (82.5% of the cases). This prevalence was 59.99% during 1 to 3 months of AIDS evolution, 81.77% during 4 to 6 months, and 100% after 6 months. The principal skin diseases were: pruritic papular eruption (33.33%), oral candidiasis (25%), herpes zoster (16.16%), hair dystrophies (13.13%), xeroderma (14.60%), furuncle (10%), seborrheic dermatitis (6.66%), Kaposi's sarcoma (5%) and recurrent folliculitis (4.16%). Thus, the skin diseases were common in AIDS patients in Lome, Togo, and tended to be more frequent as immunodeficiency progressed. Dermatological examination remains important in the detection of HIV infection and AIDS.

Acquired Immunodeficiency Syndrome↗

[Non-tumor dermatoses diagnosed in the pathologic anatomy laboratory of the Tokoin University hospital center, Lomé (Togo)].

The non-tumorous skin diseases are common in hospital consultation in tropical countries. These infections constitute a great health problem in black Africa. Their diagnosis is often clinically easy, but sometimes histologically examination is necessary to have the positive diagnosis. In Togo, a retrospective study conducted during ten years, allowed to note 516 cases of non-tumoural dermatosis which were histologically diagnosed. The principal infections were: inflammatory dermatosis 339 cases (213 cases were not specific against 108 specific cases predominated by leprosy: 82 cases), epidermal dermatosis (97 cases, predominated by eczema and psoriasis), dermal lesions (44 cases), lesions of dermic and epidermic junction (23 cases), hypodermic (13 cases). The results of this study shows the diversity of non-tumorous dermatosis diagnosed by the histology. The eradication of these diseases in Africa needs to have efficient laboratory diagnosis and research means in every country.

Dermatitis↗

[Prevalence of skin disorders associated with the use of bleaching cosmetics by Lome women].

The purpose of this study was to evaluate the occurrence of cutaneous complications among women who used bleaching cosmetics in Lomé, Togo. Of 536 women who used these cosmetics, 371 (69.2%) had at least one dermatological complication. The bleaching agents used were mercury derivatives (30.9%), hydroquinones (24%), topical corticosteroids (18.5%) and products of unknown composition (25.6%). The main dermatological side-effects were hypochromia (62.8%), hyperchromia (2.7%), melanoleucoderma (8.1%), acne (11.6%), and skin trophic disorders (14.8%). The occurrence of these complications was associated with the length of time for which the chemicals were used and the simultaneous use of different classes of these cosmetics. This study shows that dermatological complications are common in women using skin-bleaching cosmetics.

Adolescent↗

[Leg erysipelas].

Explore the source record for details and available documents.

Adult↗