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Biomedical subjects

P R Bary

Publications and source records attributed to P R Bary.

9 recordsLinked to original sources

The accuracy and limitations of ultrasound in the assessment of venous extension in renal carcinoma.

Ultrasound was used to assess venous extension in 28 patients with renal carcinoma, with particular reference to involvement of the inferior vena cava. The findings were correlated with surgical findings in all except two patients who had gross caval involvement and metastatic disease and in whom surgery was considered inappropriate. In 10 of the 28 patients (36%), a diagnostic ultrasound examination of the cava from the renal veins to the diaphragm was obtained. In four of these, ultrasound showed tumour involvement of the vena cava. In 12 cases (43%) only the intrahepatic part of the cava was seen, but the examination nonetheless excluded tumour involvement of the upper cava. Visualisation of the vena cava was impossible in six cases (21%), usually because of bowel gas or obesity; CT scanning provided valuable additional information in two of these cases. Inferior vena cavography confirmed the findings of the less invasive imaging procedures in 10 patients and was falsely positive once. Cavography is now seldom necessary in the assessment of renal carcinoma.

Aged

Bladder training--3 years on.

Fifty-six patients with the "urge syndrome" were reviewed between 1 and 5 years after in-patient treatment by bladder training. There was an overall initial cure/improvement rate of 85%. The best long-term results were obtained in those with objectively stable bladders before treatment. Forty-three per cent of patients with reduced detrusor compliance and idiopathic instability relapsed after initial improvement. Those with primary instability or with associated degenerative disease responded poorly to treatment.

Adolescent

Dynamic urethral function in the assessment of spinal injury patients.

Forty-two spinal injury patients underwent single or sequential urodynamic studies to assess the value of dynamic urethral pressure using transducer tipped catheters. Three groups of patients were identified: those with poor detrusor function, those with unsustained dyssynergia and those with sustained dyssynergia. All patients demonstrated some dyssynergia. Urethral needle EMG mirrored urethral pressure changes accurately. The addition of dynamic profilometry to fluoroscopy, detrusor pressure and urethral EMG has clarified our understanding of lower urinary tract behaviour after cord lesions.

Adolescent

The results of reflux prevention in adults with reflux nephropathy.

Twenty adult patients with varying degrees of reflux nephropathy and renal impairment were selected for anti-reflux surgery. Following reflux prevention, those patients with symptoms related to recurrent urinary tract infection were greatly improved. However, in those patients with impaired and deteriorating renal function, surgery only occasionally influences this progression. These patients all had significant proteinuria both pre- and post-operatively. Proteinuria appears to be a more significant prognostic indication of renal deterioration than the degree of reflux or reflux nephropathy.

Adolescent

Assessment for and results of urinary undiversion.

Twenty-five patients with surface diversions have been assessed for undiversion over the past 3 years. Fourteen of these have been reconstructed of which half are in the more difficult myelodysplastic group. In 7 patients renal deterioration or renal failure was the indication for undiversion. The critical factors for success are good urethral mechanism function and adequate ureteric function. All but one are subjectively pleased, and all but one have stable renal function and are continent. Infection, especially Pseudomonas, must be eliminated and careful follow-up is mandatory.

Adult

An assessment of the Frewen regime in the treatment of detrusor dysfunction in females.

Twenty-seven women with symptoms of frequency, urgency and urge incontinence were assessed urodynamically. Their detrusor behavior fell into three groups: 1. Reduced detrusor compliance, 2. Uninhibited detrusor contractions, and 3. Detrusor stability. Each patient was treated by Frewen's regime of bladder drill, detrusor inhibitory drugs, sedation and simple psychological counseling. At three months symptoms were markedly improved or cured in 86 per cent of patients. Reduced compliance was the only detrusor abnormality which was reversible.

Adolescent

Disseminated mucocutaneous herpes simplex type 2 infection in a renal transplant recipient: response to adenine arabinoside (Vidarabine).

A 27-year-old woman with a well-functioning cadaveric renal transplant presented with recurrent mucocutaneous herpes simples type two infection associated with a severe systemic illness. Two courses of treatment with adenine arabinoside (Vidarabine) were associated with rapid healing of the herpetic lesions and an improvement in her general condition. Treatment was associated with nausea but no toxic effect were noted.

Adult