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Biomedical subjects

P R Mitchell

Publications and source records attributed to P R Mitchell.

11 recordsLinked to original sources
PubMed1990

Phonetic variation in multisyllable babbling.

This investigation examined phonetic variation in multisyllable babbling of infants from 0.7 to 0.11. The basis of this investigation was to examine assumptions present in major models of infant vocal development which suggest systematic developmental increases in phonetic variation of these babbles, and posit separate stages of repetitive (multisyllables with non-varied phonetic elements) and non-repetitive (phonetically varied multisyllables) babbling. Eight infants were audiotaperecorded in their homes at ages 0.7, 0.9 and 0.11. The multisyllable vocalizations were categorized based on the presence or absence of phonetic variation, and the source of that variation (place change, manner change or both). Multisyllables were produced with phonetic variation at or near the beginning of multisyllable babbling, which failed to support the existence of distinct stages of repetitive and nonrepetitive babbling.

Humans↗
PubMed1990

Barotrauma and air embolism in hyperbaric oxygen therapy.

A 69-year-old woman underwent hyperbaric oxygen therapy because of a nonhealing ulcer of her foot. During decompression, she developed a left-sided hemiplegia and confusion. Recompression resulted in transient neurologic improvement, but she eventually became comatose. Ventricular dysrhythmias developed and she died without regaining consciousness 17 h after onset of symptoms. An autopsy revealed diffuse interstitial pulmonary fibrosis with severe paracicatricial emphysema, chronic interstitial inflammation, and chronic bronchitis with abundant intrabronchial mucus. There was extensive multifocal ischemic injury of the cerebral cortex. The hippocampi, basal ganglia, and cerebellum were spared. Scattered acute myofiber necrosis was present in the heart. Clinical presentation and autopsy findings strongly support the diagnosis of air embolism and illustrate a potential risk of hyperbaric oxygen therapy in patients with preexisting pulmonary disease.

Aged↗
PubMed1978

A proton nuclear-magnetic-resonance study of self-stacking in purine and pyrimidine nucleosides and nucleotides.

The concentration dependence of the chemical shifts of the protons H-2, H-8 and H-1' of ATP4- and of Mg(ATP)2- , of all non-labile protons of adenosine, of H-5, H-6 and H-1' of TUP, and of H-5, H-6, H-1', and H-2' of uridine have been measured. The results for the purine derivatives are consistent with the isodesmic model of indefinite non-cooperative stacking; for adenosine K = 15 +/- 2M-1, for ATP K = 1.3 +/- 0.2 M-1 and for Mg(ATP)2-K = 3.6 +/- 0.3 M-1. For the pyrimidines, uridine and TUP, stacking is much weaker and the stability constant could only be estimated; for uridine k is less than or equal to 0.5 M-1, and for UTP K approximately 0.3 M-1.

Adenosine↗
PubMedDate not supplied

Kestenbaum surgical procedure for torticollis secondary to congenital nystagmus.

The records of 48 patients with congenital nystagmus who required surgery for a significant head turn were reviewed to compare the effectiveness of the surgical techniques. Patients were omitted from the study if the last postoperative visit was less than five months following surgery, or if the surgery was for a vertical head posture. The average preoperative head turn of the 38 patients with horizontal nystagmus was 41.3 degrees with an average postoperative head turn of 11.5 degrees. The net change in head turn was 33.4 degrees. The average duration of time from surgery to final examination was four years and six months. The study was divided into six groups of patients. The first group received the Parks modification of the standard Kestenbaum procedure, the 5-6-7-8 millimeter procedure. The second group received the above procedure plus 1 mm additional surgery. The third group received another modification by Parks of 6.5-8-9-10 millimeters. The fourth group received the Calhoun and Harley modification of 40% augmentation of the original Parks recommendation, and the fifth group received 60% modification. The sixth group required more than one procedure on the horizontal recti for the abnormal head posture. The pre- and postoperative measurements are compared for each of these six groups. In some patients followed for many years, there is a tendency for a gradual return toward the preoperative head posture. In four patients in the study, the gaze preference was shifted to the opposite direction postoperatively.

Adolescent↗
PubMedDate not supplied

Analyzing ADN competencies.

El Paso Community College District, using the DACUM Process, identified 19 major competency areas with 313 specific competencies for AD Nursing. This article provides an overview of the DACUM Process, a discussion of the application to the ADN program, a summary of the results, and future activities.

Clinical Competence↗