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Biomedical subjects

P R Sill

Publications and source records attributed to P R Sill.

8 recordsLinked to original sources
PubMed1987

Gestational trophoblastic disease in Port Moresby, Papua New Guinea.

A retrospective study was performed at Port Moresby General Hospital covering the period 1.1.81-31.3.86. There were 37 cases of hydatidiform mole, 2 of choriocarcinoma and 4 of metastasizing gestational trophoblastic disease of unknown histology, During the study period there were 35,630 deliveries in the same hospital. The incidence of hydatidiform mole was found to be 1:963 deliveries. Among the patients with hydatidiform mole 1 death was recorded whilst in the group with choriocarcinoma and unclassified disease there were 4 deaths. Of the patients treated for hydatidiform mole 48.5% made no follow-up visits to the hospital.

Adolescent↗
PubMed1987

Non-obstetric female genital tract trauma in Port Moresby, Papua New Guinea.

In a 3-year period there were 25 admissions to Port Moresby General Hospital because of non obstetric injuries to the female genital tract. The injuries were caused by voluntary coitus, rape, assault and falls. The most frequent injury was a laceration to the posterior fornix of the vagina. Although rape was frequently committed in Port Moresby, it was not the major cause of genital tract injury.

Accidental Falls↗
PubMed1985

Platelet values during normal pregnancy.

Blood samples were obtained from 26 healthy women at regular intervals throughout pregnancy and analysed using a Coulter Counter Model S Plus III. The mean values for the various haematological indices at each stage of gestation were first calculated; the platelet count showed a small decrease throughout pregnancy as did haemoglobin concentration while there was an apparent increase in mean platelet volume, platelet distribution width and white cell count. However, analysis of the trends within patients did not always reflect these mean changes; there was considerable variation in platelet count within individuals and the apparent fall in the group as a whole was accounted for by a considerable fall in a few individuals. The assumption that the trends in platelet values determined from groups of patients will indicate how individual pregnant women behave is misleading.

Adult↗
PubMedDate not supplied

High frequencies of alpha-thalassaemia are the result of natural selection by malaria.

The frequency of alpha+-thalassaemia, but not other unlinked DNA polymorphisms, exhibits an altitude- and latitude-dependent correlation with malaria endemicity throughout Melanesia, supporting the hypothesis that protection against this parasitic disease is the major factor responsible for the high frequencies of haemoglobinopathies in many parts of the world.

Altitude↗