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Biomedical subjects

P R Tasker

Publications and source records attributed to P R Tasker.

4 recordsLinked to original sources

Use of co-trimoxazole in chronic renal failure.

Twenty patients with chronic renal failure and either urinary or respiratory tract infection were treated with co-trimoxazole. Seventeen patients showed no deterioration in renal function while receiving co-trimoxazole. Deterioration in renal function during treatment in the other three patients was due to factors other than administration of the drug. It is concluded that co-trimoxazole can be used in patients with chronic renal failure provided the dose is adjusted according to the degree of renal failure.

Adult

Diuretic-induced oedema.

Diuretics are now commonly prescribed for women with so-called idiopathic oedema. Two patients with idiopathic oedema, one of whom was oedematous on diuretics, had the diuretics stopped. In one the oedema became much worse, and in the other oedema developed. However, this oedema disappeared spontaneously in both patients and they have remained free of oedema on no treatment. It is suggested that in some patients treated with diuretics compensatory mechanisms to retain sodium and water may be stronger than the diuretic-effect itself and may lead to perpetuation of unnecessary treatment.

Adult