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P Rentería

Publications and source records attributed to P Rentería.

2 recordsLinked to original sources

[Affective disorders and solar activity].

INTRODUCTION: The present work discusses the link between solar activity and appearance of affective disorders. Solar activity is reflected by the Wolf number, which is given by the formula R = K (10 g + f), where g corresponds to the groups of sunspots and f is the total number of sunspots. METHODS: We examined 1,212 clinical files at the Clínica Psiquiátrica Universitaria, Santiago de Chile. Patients with major depressions and manic disorders, who were admitted to the clinic for the first time and had no previous treatment were considered. We examined the correlation between annual incidence of hospitalization and average Wolf numbers for those years, included in the period 1990-2000, which corresponds to a complete solar cycle of 11 years. RESULTS: An important number of hospitalizations of depressive patients occurred during years of low solar activity, and there was a slight increase in the number of manic patients during years of high solar activity. Depressive disorders showed a negative correlation with solar activity, the Pearson coefficient being equal to -0.72. Manic disorders showed a positive correlation, with coefficient equal to +0.334. CONCLUSIONS: Depressive disorders have an inverse correlation with solar activity, while manic disorders have a positive correlation.

Adolescent↗

[Fluoxetine in the treatment of borderline personality disorder].

OBJECTIVE: This study evaluates the therapeutic effect of fluoxetine, a selective serotonin reuptake inhibitor, in borderline personality disorder. METHOD: 46 patients with borderline personality disorder according to DSM-III-R and Diagnostic Interview for Borderlines (DIB-R) criteria, were given fluoxetine 20-60 mg for seven weeks. They were evaluated each week using Brief Psychiatric Rating Scale (BPRS), Global Assessment of Functioning Scale (GAF), Hamilton Depression Rating Scale (HDRS) and a clinical Impulsivity Scale. RESULTS: There were significant improvements in BPRS, HDRS, GAF and Impulsivity Scale from the first week of the treatment. These improvements continued until the seven week of treatment. The favourable outcome was not only due to the improvement in depression and impulsivity scores, but also to the decline of global psychopathology. CONCLUSIONS: The data suggest that fluoxetine is an effective pharmacologic treatment for borderline personality disorder. These findings support the hypothesis of a 5-HT dysfunction in borderline personality disorder.

Adolescent↗