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Biomedical subjects

P Reuther

Publications and source records attributed to P Reuther.

16 recordsLinked to original sources
PubMed2004

[Doctor reports of a neurological clinic in the view of permanent resident neurologists and nerve doctors].

Eight discharge reports involving five diagnoses (anterior territory ischemic stroke, epilepsy, Parkinson's syndrome, multiple sclerosis, polyneuropathy) from five neurological departments were peer-reviewed by five neurologists working in out-patient (private) practice. The review considered the diagnosis, case history, clinical status, laboratory investigation, differential diagnosis and treatment. Criticism mainly involved the quality of the clinical assessment, lack of clinical status at discharge, narrow or incomplete differential diagnosis and the quality of the neurophysiological investigations for epilepsy and polyneuropathy. Improvement potential was seen for the speed of reporting, better comprehensibility, omission of irrelevant information, greater participation of experienced neurologists in report writing, and standardization.

Ambulatory Care Facilities↗
PubMed1999

[Continuing medical education (CME) in neurology. Concept of the German Society of Neurology (DGN) and the Neurology Section of the Professional League of German Neurologic Medicine (BVDN)].

Continuous medical education in Neurology (CME-Neurology) has been promoted in a concept organized by both the German society of neurology, German association for occupational interests of neurologists and psychiatrists). CME-Neurology has been started in January 1999 and is closely adapted to the CME guidelines of neurology section of UEMS and EFNS. The program shall serve to the maintenance and upgrading of knowledge skills and competence of postgraduate training in neurology.

Education, Medical, Continuing↗
PubMed1985

Splenectomy in myasthenia gravis: a therapeutic concept?

The case histories are presented of five patients with long-diagnosed myasthenia gravis (up to 15 years) who underwent splenectomy. A precondition for the decision to operate was muscle weakness that could not be controlled with standard therapy (e.g. anticholinesterase drugs, immunosuppressive measures). After splenectomy, a considerable improvement took place in three cases; in one case there was moderate improvement, and in another, no improvement. The alleviation of myasthenia gravis may be attributable to the reduction of either the number of immunocompetent lymphocytes in an important storage organ or of the total bulk of the immune system in an immune disease with raised auto-antibody production. The acetylcholine receptor antibody titre was not affected by the operation in a consistent way. After splenectomy, immunosuppressive medication was tolerated better with respect to its haematological side-effects.

Adult↗
PubMed1984

[Myasthenia gravis. Information for the anesthetist and critical care physician].

Myasthenia gravis is an autoimmune-disorder and clinically characterised by weakness of voluntary muscles including respiratory and pharyngeal muscles. As myasthenia gravis is a rare disease surgeons and anesthesiologists are only seldomly confronted with patients suffering from this disease. However, the application of narcotics or of other drugs may lead to the manifestation of a subclinical form of myasthenia gravis or provoke a critical exacerbation of the patient's condition with severe respiratory and bulbar dysfunction. This paper describes guidelines for the use of narcotic drugs or other pharmacotherapy in myasthenia gravis patients. On the other hand this paper gives information about the intensive care and management of patients suffering from myasthenic of cholinergic crisis, which is known to be a lifethreatening emergency. Finally, the paper describes shortly the long-term treatment with immunosuppressive or immunoregulatory measures.

Adult↗
PubMed1983

Autonomic dysfunction in polyneuropathies: a report on 106 cases.

Autonomic dysfunction is a common feature in various forms of polyradiculoneuropathy. This study investigated the kinds and frequency of of autonomic dysfunction in 106 cases. Denervation insufficiency of organs associated with supersensitivity of reflex mechanisms was found to be the best explanation of the pathophysiology. Early insertion of a transient cardiac pacemaker is recommended to counteract life-threatening cardiac failure.

Autonomic Nervous System Diseases↗
PubMed1979

[Treatment of myasthenia gravis with plasmapheresis (author's transl)].

Nine out of eleven severely ill patients with myasthenia gravis could be markedly improved by a combination of immunosuppressive drug therapy and plasmapheresis, two patients however suffered grave complications. The effectiveness of plasma exchange underlines the importance of plasma factors in the pathomechanism of myasthenic functional disturbance. Treatment with plasmapheresis may be regarded as a supportive measure of immunosuppressive drug therapy. However, the considerable risk and high technical requirements limit the indication to severe forms of the disease.

Adolescent↗