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Biomedical subjects

P Revsbech

Publications and source records attributed to P Revsbech.

7 recordsLinked to original sources
PubMed1992

Is sarcoidosis related to exposure to pets or the housing conditions? A case-referent study.

On the assumption that sarcoidosis could be caused by inhalation of antigens stemming from pets a case-referent study was set up to examine this idea. Thirty-nine patients with biopsy-proven sarcoidosis were compared with 106 sex- and age-matched control persons on the exposure to pets, present and previous, in the households. In addition data on basic housing conditions and smoking habits were collected. No statistical difference in the absolute frequency of dogs, dogs and/or cats or any pet in the two groups was observed counting only pets kept for more than 2 years prior to the year of diagnosis. Equally the basic housing conditions (size, type of and age of dwelling, family size) were identical. There was a tendency of more non-smokers in the sarcoidosis group (46% vs 33%) but the difference did not reach statistical significance. However it cannot be excluded that inhalable antigens stemming from pets initiate sarcoidosis among susceptible individuals.

Adult↗
PubMed1990

Storage mite allergy among bakers.

Allergy to storage mites has been shown among farmers and grain elevator workers. This study aimed to examine whether bakers also are sensitized to storage mites. Twenty-three bakers or other employees in bakeries suffering from nasal or pulmonary symptoms were compared with 17 control persons with no relation to bakery work or agriculture. All participants underwent skin prick test with a standard panel of allergens, four types of flour and the storage mites Acarus siro, Lepidoglyphus destructor and Tyrophagus putrescentiae, RAST to storage mites and flour, and measurement of total IgE. We found no difference between the baker group and the control group in prevalence and strength of positive skin prick test or RAST to any of the three storage mite species. In the baker group positive RAST to flour was related to positive RAST to A. siro and L. destructor, but not T. putrescentiae. Almost all bakers sensitized to flour were also sensitized to storage mites (6 of 7). We suggest that if a baker become sensitized to flour he will be more prone to develop specific IgE towards storage mites too.

Animals↗
PubMed1989

Diurnal variation in peak expiratory flow rate among grain elevator workers.

The diurnal variation (DV) in peak expiratory flow rate (PEFR) has been studied among 132 grain elevator workers who accomplished three daily measurements of PEFR during three weeks. DV was calculated as the difference between the highest and the lowest PEFR as a percentage of the mean PEFR on each day. For the whole group the median was 5.9%. DV was higher among smokers and among workers with work related pulmonary symptoms. Analysis of variance showed that only age (p = 0.012) and smoking (p = 0.016) had a significant effect on DV. Pulmonary symptoms, total IgE, and duration of occupation had no independent impact on DV, whereas the exposure level of grain dust tended (p = 0.082) to have an independent effect. Twelve workers had an abnormally high DV (greater than 20%), of whom seven showed no signs of obstructive respiratory disease by spirometry. If only a single spirometric test had been performed the tentative diagnosis of bronchial asthma could have been missed in these seven workers.

Agriculture↗
PubMed1987

Storage mite allergy among grain elevator workers.

A total of 139 workers (71% of the available work force) in four grain elevator stores in Aalborg, Denmark, participated in a cross-sectional study on the prevalence of storage mite allergy among grain elevator workers. All underwent interview, prick test with a standard panel of allergens and the storage mites Acarus siro, Lepidoglyphus destructor and Tyrophagus putrescentiae, RAST to the three above-mentioned storage mites plus Glycyphagus domesticus and wheat, measurement of serum total IgE, and spirometry. Pulmonary symptoms were present among 44%, nasal and eye symptoms among 48%. Thirty-one per cent complained of work-related respiratory symptoms. Fourteen per cent of these workers had only nasal symptoms. Comparing the prick test result and the history, 6.4% had respiratory storage mite allergy, while 15.9% were sensitized to storage mites. Storage mites seem to be the most important allergen among grain elevator workers in Denmark. Faunistic examination of samples of grain and dust showed that storage mites, in particular A. siro, L. destructor and T. longior, were found in 73% of grain samples, while all dust samples contained mites.

Adult↗