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Biomedical subjects

P Reznitsky

Publications and source records attributed to P Reznitsky.

3 recordsLinked to original sources

Neonatal manifestations of congenital dyserythropoietic anemia type I.

Congenital dyserythropoietic anemia type I is a rare inherited bone marrow disorder characterised by macrocytic anemia with pathognomonic morphological ultrastructural features in erythroid precursors. The disease is usually not diagnosed in the neonatal period. In a retrospective study of 31 patients we found that 17 were first seen in the neonatal age with significant anemia (birth hematocrit 0.34 +/- 0.07); 14 of the 17 infants also had early jaundice. Six infants were small for gestational age and two had syndactyly. Although rare, congenital dyserythropoietic anemia type I should be considered in the differential diagnosis of neonatal anemia.

Anemia, Dyserythropoietic, Congenital↗

[T-cell lymphoma].

8 patients with lymphoproliferative disorders of T-cell origin were diagnosed during the years 1985-1987. They included 2 cases of so-called Lennert's lymphoma, 1 case of T-cell lymphoma simulating malignant histiocytosis and 1 case of T-cell lymphatic lymphoma with splenic T-cell lymphoma which survived 10 years. The other cases presented with peripheral T-cell lymphomas. Immunologic typing of malignant lymphomas with cell suspensions is of diagnostic value.

Diagnosis, Differential↗

Unusual clinical presentation of acute sarcoidosis.

A 16-year-old male developed fever and productive cough of 2 months' duration. Extensive search for an infectious process was negative. After appearance of knee joint effusion, a transbronchial biopsy through a fiberoptic bronchoscope revealed histological findings consistent with sarcoidosis. The patient recovered after a course of prednisone therapy. The atypical presentation of this systemic disease caused considerable delay in diagnosis and initiation of treatment.

Acute Disease↗