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Biomedical subjects

P Richez

Publications and source records attributed to P Richez.

16 recordsLinked to original sources
PubMed2005

[Multivisceral tuberculosis with aortic complication in an immunocompetent patient].

The medical and imaging data of a 59 year old male is reported. The patient presented with cough, fever, night sweats and weight loss, for which a final diagnosis of multivisceral tuberculosis (with peritoneal involvement and mycotic aneurysm) was made, by means of CT, MRI and laparoscopic findings. This disease is uncommon in developed countries with subjects lacking the usual risk factors. Because delayed treatment may be lethal, especially with such serious vascular complication, the authors review the value and limitations of CT and MRI along with the suggestive features.

Aortic Aneurysm, Thoracic↗
PubMed1999

[Pilocytic astrocytoma of the conus medullaris].

We report the case of a rare glial tumor of the conus medullaris classified as pilocytic astrocytoma in a young adult. This tumor is most commonly found in the brain. The imaging findings will be correlated with the findings at histology. The literature will also be reviewed.

Adult↗
PubMed1998

[Ureteral hematoma complicating anticoagulant treatment].

Submucosal hemorrhage of the ureters, are a very uncommon quoted cause of hematuria when overdosing anticoagulants. We report two cases, CT shows some very typical aspects but can also highlight, as reported formerly, another associated complication: parietal hematoma of the small bowel.

Aged↗
PubMed1998

[An MRI study of primary testicular tumors].

Magnetic resonance imaging (MRI) is a high performance tool for morphological assessment and tissue characterization in the presurgical work-up of scrotal tumors. A wait-and-see attitude is now possible for benign lesions identified as epidermoid cysts. Pathology examination remains more pertinent for an exhaustive assessment of local extension, but MRI can provide a convincing, if not definitive, distinction between seminomatous and non-seminomatous germ cell tumors.

Adolescent↗
PubMed1998

[Osteoarticular involvement in parasitic diseases: bone echinococcosis].

Hydatid disease is the most common human disease caused by helminths, but primary skeletal involvement is uncommon. Diagnosis is usually obtained late after considerable extension, half of which concerns the spine. The dissemination mode leads to local malignancy with severe prognosis. Medical imaging is essential. Plain x-ray findings are polymorphous and nonspecific, but computed tomography and magnetic resonance imaging are particularly useful for exhaustive pretherapeutic assessment of extension and for patient follow-up.

Bone and Bones↗
PubMed1998

[Osteoarticular involvement in parasitic diseases: bone mycetoma].

Mycetoma remains a common pathology in tropical areas. Diagnosis, based on mycology and pathology is still frequently late and treatment often leaves severe functional disorders. Medical imaging is indispensable to evaluate disease spread to bone tissue. Plain radiograms usually show cortical erosion, defects with sclerosing margins, and bone thickening. CT is the most sensitive technique to detect bony involvement. CT and MR imaging, when available, are the most accurate techniques for determining disease extension in both bones and soft tissues.

Bone Diseases, Infectious↗
PubMed1998

[Osteoarticular involvement in parasitic diseases: bone treponematosis].

Bone and joint localizations of treponematosis vary greatly although there are many common features. Osteal and periosteal lesions are common. We report radiographic descriptions of bone and joint treponematosis, which must not go unrecognized due to the increasing incidence of these diseases.

Bone Diseases, Infectious↗
PubMed1990

Assessment of anti-phenolic glycolipid-I IgM levels using an ELISA for detection of M. leprae infection in populations of the South Pacific Islands.

Anti-phenolic glycolipid-I (PGL-I) IgM levels were determined in 96% of the general population of the Southern Marquesas and Maupiti, remote islands of French Polynesia, where the average annual detection rates of leprosy during the past 30 years have been 57.1 and 4.4 per 100,000, respectively. The seropositivity in these two areas was 4.3% and 4.2%, respectively. No significant difference (p greater than 0.05) was found between either these two figures or between the percentages of persons with high (greater than or equal to 0.500 OD) anti-PGL-I IgM levels (9.2% and 5.3%). In the two islands, the age distributions of anti-PGL-I IgM were very similar; the percentage of positive responders was higher in females than in males and higher in adolescents than in adults. These results suggest that the usefulness of the determination of anti-PGL-I IgM levels by ELISA, using the synthetic trisaccharide as antigen, for detecting Mycobacterium leprae infection in leprosy control programs is extremely doubtful.

Adolescent↗
PubMed1982

Drug immunotoxicological approaches with some selected medical products: cyclophosphamide, methylprednisolone, betamethasone, cefoxitine, minor tranquillizers.

Alterations of the normal immune response were estimated in C57B1/6 mice pretreated with cyclophosphamide, methylprednisolone sodium succinate, betamethasone sodium phosphate or cefoxitine as positive controls and three minor tranquillizers: dipotassium chlorazepate, diazepam and meprobamate. The specific immune response against sheep red blood cells (SRBC) was evaluated by numeration of the direct plaque-forming cells (PFC; humoral immunity) and by measurement of the footpad swelling (delayed-type hypersensitivity, DTH). In our experiments, the results with the positive controls were in the same order as those described by others, and at the dose levels used, these three minor tranquillizers did not really alter the specific humoral and cellular immune response against SRBC in the C57B1/6 mice.

Animals↗
PubMed1980

[Veterinary anesthesiology, a pharmacological model (author's transl)].

Different mechanisms are involved in drug interactions, especially between anesthetics and drug administrated before and during anesthesia: liver disease, bioavailability related to the route of administration, displacement of the protein-bound of the part, etc. Two peculiarities of veterinary anesthesiology were found useful to evaluate such drug interactions: changes in the frequency of the cyclic contraction of the reticulum (sheep) and decrease in the central body temperature (cat). These criteria were used in addition to electroencephalographic recordings to appreciate the inhibition of microsomal penthiobarbital metabolism by chloramphenicol, the effect of phenylbutazone on plasma-protein displacement and the non-bioavailability of chloramphenicol by the subcutaneous route.

Anesthesia↗
PubMedDate not supplied

Pharmacokinetics of doxycycline after parenteral administration in the Houbara bustard (Chlamydotis undulata).

Fourteen adult Houbara bustards (Chlamydotis undulata) infected with Chlamydia psittaci were administered doxycycline at 100 mg/kg body weight in seven intramuscular or subcutaneous injections at intervals of 7, 7, 7, 6, 6, and 5 days. Blood levels of doxycycline were measured after the first and seventh injections at the following intervals: 0, 12, 24, 36, 48, 72, 96, 120, 144, 168, and 180 hours. During these two periods, most of the birds showed plasma doxycycline levels in excess of 1 micrograms/ml, demonstrating effective doxycycline levels for 45 days. A multifactorial analysis of variance revealed no significant differences between males and females, between the two routes of administration, or among all four factors.

Animals↗