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Biomedical subjects

P Riis Hansen

Publications and source records attributed to P Riis Hansen.

3 recordsLinked to original sources

Septal alcohol ablation and Heyde's syndrome revisited.

We describe a 57-year-old male with hypertrophic obstructive cardiomyopathy and occult blood loss. Septal alcohol ablation reduced the left ventricular outflow tract obstruction and eliminated recurrent bleeding. The case resembles Heyde's syndrome, i.e. the association between occult gastrointestinal bleeding and aortic valve stenosis, where resolution of blood loss after corrective aortic valve surgery has also been reported.

Cardiomyopathy, Hypertrophic↗

Induction of oxygen free radical generation in human monocytes by lipoprotein(a).

The mechanism behind the association of elevated plasma lipoprotein(a) [Lp(a)] levels with atherosclerotic disease is unknown. In the present study, Lp(a) induced generation of oxygen free radicals by monocytes from selected healthy individuals in vitro. This observation may provide a link between Lp(a) and generation of oxidized LDL, which can promote multiple atherogenic cellular responses.

Female↗

Egg consumption and high-density-lipoprotein cholesterol.

OBJECTIVES: To examine if increased egg consumption raises serum high-density-lipoprotein (HDL) cholesterol in healthy individuals. DESIGN: A cross-over study. SETTING: A private clinic for preventive health examinations in Copenhagen. SUBJECTS: Twenty-four healthy adults, 12 men and 12 women, aged 23-52 (median 40) years. INTERVENTIONS: After a 1-week control period each person added two boiled eggs to the usual daily diet for 6 weeks. All persons were instructed not to change the lifestyle in other ways during the whole study period. MAIN OUTCOME MEASURES: Serum HDL cholesterol, total cholesterol and triglycerides were measured before, during and after 6 weeks of extra egg consumption. The corresponding serum low-density-lipoprotein (LDL) cholesterol was calculated from the Friedewald formula. RESULTS: After 6 weeks of extra egg consumption serum HDL cholesterol increased by 10% (P < 0.05) and total cholesterol increased 4% (P < 0.05), whereas the ratio total cholesterol/HDL cholesterol did not change significantly. Serum triglycerides and LDL cholesterol were also unchanged. CONCLUSIONS: A moderate egg intake should not be rigorously restricted in healthy individuals.

Adult↗