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Biomedical subjects

P Rios

Publications and source records attributed to P Rios.

7 recordsLinked to original sources
PubMed2001

Real-life-type problem-solving in Asperger's syndrome.

This study compared adolescents with Asperger's syndrome with typically developing adolescents on a novel problem-solving task that presented videotaped scenarios in real-life-type social contexts. The Asperger's group was impaired in several aspects of problem-solving, including recounting the pertinent facts, generating possible high-quality problem solutions, and selecting optimal and preferred solutions. This group's solutions differed most from those of the typically developing group in social appropriateness. The contributions of social experience, social understanding, and executive skills to performance on the novel problem-solving task are discussed.

Adolescent↗
PubMed2001

Afro-American migrant farmworkers: a culture in isolation.

Increasing rates of HIV infection have been found in migrant farmworkers in the USA over the past decade. By virtue of lifestyle, language and culture, these workers are not exposed to the typical media HIV prevention messages. To determine their level of knowledge about this disease for use in prevention messages targeted specifically to this population, five gender specific focus groups were conducted among Haitian, Jamaican and African-American migrant farmworkers in upstate New York. The focus groups revealed that the health belief system of these Afro-American migrant workers primarily reflects that of their indigenous culture. This impacts their interpretation and utilization of risk aversive behaviours. The data also suggest that the culture of migrancy itself affects the extent of risky behaviours practised, but further studies are needed to examine this phenomenon.

Adult↗
PubMed1994

A case-control family history study of autism.

Family history data on 99 autistic and 36 Down's syndrome probands are reported. They confirmed a raised familial loading for both autism and more broadly defined pervasive developmental disorders in siblings (2.9% and 2.9%, respectively, vs 0% in the Down's group) and also evidence for the familial aggregation of a lesser variant of autism, comprising more subtle communication/social impairments or stereotypic behaviours, but not mental retardation alone. Between 12.4 and 20.4% of the autism siblings and 1.6% and 3.2% of the Down's siblings exhibited this lesser variant, depending on the stringency of its definition. Amongst autistic probands with speech, various features of their disorder (increased number of autistic symptoms; reduced verbal and performance ability) as well as a history of obstetric complications, indexed an elevation in familial loading. No such association was seen in the probands without speech, even though familial loading for the lesser variant in this subgroup, was significantly higher than in the Down's controls. The findings suggest that the autism phenotype extends beyond autism as traditionally diagnosed; that aetiology involves several genes; that autism is genetically heterogeneous; and that obstetric abnormalities in autistic subjects may derive from abnormality in the foetus.

Adolescent↗
PubMed1990

Primary structure of Trypanosoma cruzi small-subunit ribosomal RNA coding region: comparison with other trypanosomatids.

A Trypanosoma cruzi small subunit ribosomal RNA gene was sequenced from genomic recombinant plasmid clones. The assigned coding region was 2319 bp, the longest SSU rRNA gene described to date. On the basis of comparisons with published sequences from Crithidia fasciculata, Trypanosoma brucei, and Leishmania donovani, we conclude that the extra nucleotides in the T. cruzi gene occur in highly variable regions of rRNA genes. A phylogenetic analysis was performed with the SSU rRNA sequences from these four trypanosomatids and from Euglena gracilis as an outgroup. The Leishmania and Crithidia sequences were remarkably similar to each other (not separable statistically). Given the standard errors associated with the branching order of the two Trypanosoma species and the Leishmania-Crithidia branch, the actual topology cannot be unequivocally determined using only the ribosomal sequences analyzed here.

Animals↗
PubMed1989

Autism diagnostic interview: a standardized investigator-based instrument.

The development of a new standardized investigator-based interview for use in the differential diagnosis of pervasive developmental disorders is described, together with a diagnostic algorithm (using ICD-10 criteria) based on its use. Good interrater reliability for algorithm items was shown between four raters, two in Canada and two in the UK, who rated 32 videotaped interviews. The items also significantly discriminated between 16 autistic and 16 nonautistic mentally handicapped subjects. The algorithm based on ICD-10 identified all 16 autistic individuals and none of the 16 nonautistic subjects.

Adolescent↗
PubMed1989

Recognition and expression of emotional cues by autistic and normal adults.

High-functioning autistic adults were compared with normal adults using a battery of tests devised to assess the recognition and expression of emotional cues in both facial and vocal modalities. The autistic subjects were relatively impaired in both the appreciation and production of emotional expressions. Although no one test provided a clear-cut separation of the groups at the individual level, composite scores did separate the groups quite well. It is suggested that this battery of tasks may have some value in family genetic studies of autism that need to identify subclinical deficits that might be aetiologically linked with autism.

Adult↗