[Reduced lymph drainage after pelvic lymph node excision].
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Biomedical subjects
Publications and source records attributed to P Riss.
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This case report describes successful IVF of oocytes of a 22-year-old female with epididymal spermatozoa aspirated from alloplastic spermatocele of the husband presenting with bilateral congenital absence of the vas deferens. Motile spermatozoa were aspirated from the reservoir 3 months after implantation. Abortion occurred 22 days after embryo replacement.
In early 1989, we sent a questionnaire to all 89 Departments of Gynaecology in Austria. Questions covered the number and type of gynaecological operations performed, perioperative management, and diagnosis and treatment of descent and urinary incontinence. 90% of questionnaires were returned. We found that currently 2/3 of all hysterectomies and 9/10 operations for descent and incontinence are done vaginally, irrespective of the size of the department. There was no relationship between the frequency of vaginal hysterectomies and the percentage of vaginal operations for descent and incontinence. Suprapubic bladder drainage is used in over 50%, in 85% postoperative screening for urinary tract infection is done routinely, and 53% of departments use prophylactic antibiotics. We conclude, that vaginal hysterectomy is still the method of choice in Austria, and that there is extreme emphasis on vaginal operations for urinary incontinence.
In the last 10 years, 12 abdominal metroplasties (Tompkins) were performed at the 2nd Department of Obstetrics and Gynaecology, Vienna. All patients had a history of at least 2 spontaneous abortions, caused by a deformity of the uterus. The operation according to Tompkins, is technically simple and does not result in a defect in the uterus. There were no intraoperative or postoperative complications. Follow-up was possible in 10 patients, 8 of whom had a persisting wish for a child. 5 of these women became pregnant again, one had an abortion. All children were delivered by elective Caesarean section after the 36th week; the fetal outcome was satisfactory. In our experience, Tompkins' operation is the surgical therapy of choice in habitual abortion cause by Müllerian anomalies.
Current practice of investigating abnormal uterine bleeding via dilatation and curettage is sometimes open to question, and outpatient procedures are emphasised. The therapeutic effect of curettage in normalising menstrual patterns is being discussed. In a prospective study we answered the question of diagnostic and therapeutic effects of curettage. Over a period of 6 months, all patients with curettage treated in our department were investigated (history, risk factors, previous hormonal treatment, preoperative haemoglobin value, type of anaesthesia, complications, histology). Curettages performed for the purpose of abortion, as well as in combination with conisation of the uterine cervix, were not included in the study. 234 curettages were carried out. Clinical indications were as follows: in 29% of the cases recurrent preclimacteric metrorrhagia, in 27% climacteric metrorrhagia, in 24% PMB (postmenopausal bleeding). In 19 cases we found an Hb value lower than 10.5 g%. Risk factors (obesity, hypertension, diabetes mellitus) for endometrial cancer were found in 38% of MB and in 20% of climacteric metrorrhagia. In 9 cases, the histological diagnosis was endometrial cancer (clinical indications: 5 PMB, 3 climacteric metrorrhagia, 1 recurrent preclimacteric metrorrhagia). Our study shows, that the indication for curettage should be applied generously, especially in cases of abnormal postmenopausal and perimenopausal bleeding.
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We developed a simple menu driven database on a personal computer for classification and documentation of vulvar lesions (IBM-PC, dBaseII). Vulvar lesions were classified according to morphological appearance: red, white, dark, ulcer, small tumor (less than 1 cm), large tumor. The data for each category were entered in multiple choice form or as free text and stored in a separate database file. Overlap between categories was observed in vulvar intraepithelial neoplasia, invasive carcinoma and between large and small tumors. For each category an automated table of the frequencies of the different diagnoses is provided, individual patients and variables can easily be accessed through the database query language. We used the database system in the gynecological outpatient clinic of our department during 6 months and were able to document 117 patients with vulvar lesions. In our experience, the database system permits complete documentation according to clinical criteria of all vulvar lesions seen in gynecological practice.
Gonadotropin releasing hormone (GnRH) agonists can induce a hypogonadotropic state. We studied the effect of a long acting GnRH agonist on pituitary gonadotropin levels, the pattern of serum steroid levels in subsequent cycle stimulation, and whether such a protocol can improve the results of an in-vitro fertilization (IVF) program. 29 patients with tubal factor from our IVF program received 4 mg Decapeptyl CR intramuscularly and were subsequently stimulated with FSH/HMG/HCG (Group I). 35 patients were stimulated according to our standard protocol with HMG/HCG (Group II). After a single injection of Decapeptyl CR, serum levels of LH, FSH and E2 fell to more than half of pretreatment levels. In the subsequent cycle stimulation the gonadotropin dosage was increased threefold compared with the control group. In group I, progesterone levels were significantly higher. Though more oocytes were retrieved in group I, fertilization rates were significantly lower. After Decapeptyl and the subsequent stimulation, we observed short rises in urinary LH in 22/29 patients. In our experience, a single intramuscular injection of Decapeptyl resulted in sufficient pituitary suppression, however, we could not see an improvement in the results after IVF.
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In order to analyse the decisions used in non-urodynamic preoperative diagnosis of female urinary incontinence we constructed a decision tree, consisting of decision nodes and probability nodes. Each branch of the decision tree leads to an end point (terminal node), to which an utility must be assigned. We describe the different steps in the construction of the decision tree: 1. listing of all possible decisions (questionnaire, clinical stress test, both, no preoperative tests), 2. assignment of probabilities to the different events (e.g. cure, failure, operation in the absence of genuine stress incontinence), and 3. assignment of utility factors to the end points. We used previously published probabilities from our clinic, utility was assigned arbitrarily using a score from -10 to +90. The decision tress allows not only the calculation of the strategy with the highest expected utility, but also threshold analysis, sensitivity analysis and cost-benefit analysis. We feel that decision trees are valuable tools for analysing how medical decisions are reached and are particularly useful in teaching situations.
56 women underwent vaginal repair because of primary genuine stress incontinence. Urodynamic investigation was carried out preoperatively and 10.9 (7-13) months after surgery. At follow-up continence was demonstrable in 44/56 patients (79%). Detrusor instability following surgery for stress incontinence was found in 2/56 patients (4%). Vaginal repair failed to rectify stress incontinence in 21% of the patients. In cured patients the postoperative urethral pressure profile at rest remained unchanged, while the postoperative urethral closure pressure profile during stress significantly increased in these patients. In incontinent patients following surgery the urodynamic parameters of both pressure profiles correlated well with the severity of the incontinence.
In order to assess the incidence and type of urologic complications associated with Wertheim's radical hysterectomy we studied all 154 patients undergoing radical hysterectomy at our department between 1980 and 1986. More than 2/3 of patients had stage I carcinoma of the cervix, the mean age was 46.9 years (range 27-73 years). Various intraoperative reconstructive procedures were required in 5%. A comparison with the experience of Wertheim (before 1919) and that of a subsequent time period (1952-1967) showed that while the incidence of intraoperative injury to the lower urinary tract remained stable, the incidence of postoperative fistula formation decreased significantly (from 6.4% to 0.6%), possibly due to changes in the operative technique. We conclude that Wertheim's radical hysterectomy now involves only a very low risk of injury to the bladder or to the ureter.
We report on a case of true ovarian pregnancy, and discuss the anatomical criteria required for the diagnosis of this rare type of ectopic pregnancy.
In this study we examined the therapeutic effect of impulse-galvanization in patients with voiding difficulties after anterior vaginal repair. Patients (n = 56/79) revealing residual urine until the sixth postoperative day were studied. Considering the onset of the first spontaneous micturition and the lack of residual urine no significant difference was found in the group undergoing impulse-galvanization (n = 19) compared to a group without therapy (n = 37). By adjuvant treatment with alpha-sympathicolytics, spasmolytics or tranquilizers patients with impulse-galvanization and the comparative group were found to be without residual urine 11.2 and 13 days after surgery, respectively (p less than 0.001).
We analyzed the significance of weight and various indices of relative weight in the assessment of genuine stress incontinence (GSI) in 193 female patients. Body mass index [BMI = weight/(height2)] and the other indices of relative weight [weight/height - weight/(height3)] were not markedly different between patients with GSI and a control group of 43 females without demonstrable incontinence. A markedly increased BMI was found to be correlated with a positive clinical stress test. In addition BMI was significantly higher in patients with a higher maximum urethral pressure. We conclude that although obese women tend to have higher maximum urethral pressures, this advantage disappears in regard to the maximum urethral closure pressure, resulting in a higher prevalence of positive clinical stress test.
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