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Biomedical subjects

P Rodesch

Publications and source records attributed to P Rodesch.

At least 19 recordsLinked to original sources
PubMed1990

Caustic ingestion and esophageal function.

The aim of the present study was to investigate esophageal motor function by means of krypton-81m esophageal transit scintigraphy and to compare the results with the functional and morphological data obtained by means of triple lumen manometry and endoscopy. In acute and subacute stages of the disease, all clinical, anatomical, and functional parameters were in good agreement, revealing significant impairment. In chronic stages, the severity of the dysphagia was not correlated to the importance of the residual stenosis. Conversely, 81mKr esophageal transit and manometric's findings were in good agreement with the clinical symptoms, during the entire follow-up period ranging between 3 months to 7 years. The 81mKr test is undoubtedly the easiest and probably the most physiological technique currently available for long-term functional evaluation of caustic esophagitis.

Accidents, Home↗
PubMed1987

Gastro-oesophageal reflux in paediatric patients: studies with alizapride.

A series of studies was carried out in infants and children suffering from gastro-oesophageal reflux to assess the therapeutic efficacy and tolerability of alizapride, a recently developed dopaminergic-receptor blocker. Investigational techniques such as manometry, pH monitoring, endoscopy and scintigraphy were used to evaluate a prokinetic activity of the drug and its effects on oesophageal and gastric motility when given by the intravenous and oral routes. Preliminary findings indicate that alizapride had a significant effect on lower oesophageal sphincter pressure and peristaltic wave amplitude, but the evidence for an effect on gastric motility was less clear. Long-term treatment with oral alizapride (usually in a dosage of 5 mg/kg/day) suggests that it produced marked symptomatic improvement and was very well tolerated in the majority of the patients studied. A double-blind controlled trial is now in progress to provide more objective evidence of the usefulness of alizapride in the management of digestive tract motor disorders in paediatric patients.

Adolescent↗
PubMed1986

Sonographic demonstration of malabsorption in neonates.

A new sonographic pattern is described that has been found in eight infants having syndromes associated with malabsorption. Five infants had hepatobiliary disease and three infants had transient or permanent cow-milk intolerance. In all cases, upper abdominal sonographic examinations revealed hyperechoic tubular and round masses which, most probably, represent small bowel loops filled with malabsorbed milk. Control examinations, before hepatic failure or under corrected diet, showed absence of the pattern. It is believed by the authors that in some ambiguous cases, the finding of this pattern should direct the pediatrician toward syndromes associated with malabsorption.

Bile Ducts↗
PubMed1985

Evaluation of esophageal transit in children and in infants by means of Krypton-81m.

This paper presents the results of Krypton-81m esophageal transit study in a series of children and infants presenting various esophageal disorders. The advantage of Kr-81m, compared to other radionuclides, is that the radiation dose to the patient is extremely low. The study can therefore be repeated as often as necessary and a high dose can be given to ensure good quality results. The method is very easy to perform and allows a quantitative assessment of esophageal transit in physiological conditions. The method gives information about the severity of altered transit and it is particularly useful in studying the effects of treatment.

Adolescent↗
PubMed1982

Gastroesophageal scintiscanning in children.

Four patients' positions were tested in search of increased sensitivity of gastroesophageal scintiscanning for the detection of reflux in children: supine, prone, left lateral, and 30 degrees right posterior oblique. The sensitivity was highest when the child was placed in supine position. A 60-min recording period increased the sensitivity of the technique, and is thus preferred to a shorter recording time.

Child↗
PubMed1981

Gastro-oesophageal scintiscanning in children.

99mTc colloid scintigraphy is a sensitive technique for the detection of gastro-oesophageal reflux, compared to X-ray studies. A quantification index of reflux is used and can be of value when there is concern about the significance of a positive result. Continuous monitoring during one hour increases by 25% the detection of reflux in comparison with a 30 min test. In our series, no case of lung aspiration was recognized using this technique. The scintiscanning index cannot predict the existence of an associated oesophagitis.

Barium↗
PubMed1977

Fiberendoscopy of the gastrointestinal tract in children. A series of 100 examinations.

This article reports the results of our first 100 examinations of the upper gastrointestinal tract and the colon in children and infants, using standard fiberscopes and also pediatric models. The procedure could be performed under sedation in 80% of the cases and general anesthesia was required mainly with standard fiberscopes. Compared to roentgenographic findings, fiberendoscopy proved to be more reliable in superficial mucosal lesions and gastrointestinal bleeding. Colonoscopy though difficult, is valuable in diagnosing rectal bleeding lesions and as a follow-up technique in inflammatory bowel diseases.

Abdomen↗
PubMed1977

Fiberendoscopic monitorised dilatation of oesophageal strictures in children.

Oesophageal dilatations were performed 55 times in 10 children aged 2 months to 8 years presenting with acquired strictures of several origins. Classical bougienage with rubber material and newer technique with the Eder-Puestow's metallic olives system were used successively. The conjunction of the latter with systematic use of fiberendoscopy enhances considerably the safety of the procedure and permits better functional results.

Child↗