Biomedical subjects
Publications and source records attributed to P Romanet.
The authors report their exploration's test of efferent pathway through the BERA with the wave one's surface... Thirty one subjects have been tested. If we can deduce through this study the interaction of the two cochlea by efferent pathway.
The otorhinolaryngologic (O.R.L.) diseases seen in the emergency room are frequent and diverse. Most of them need the otorhinolaryngologist and anaesthetist to be present in order to realise fast, adequate and, above all, well coordinated gestures. The foreign bodies, the hemorrhagies, the traumas, the infectious diseases and finally the respiratory distress can be classified by frequency order. The laryngo tracheal dyspneas (DL) are first considered because they are the most dramatic emergencies: infectious DL in children, DL secondary to tracheal intubation or tracheotomy, DL caused by a tumor, traumatic DL secondary to a knock, a blast, a burn or a thyroidectomy, edematous DL and "DL after tracheotomy". The infectious O.R.L. emergencies are observed in the serious pharyngeal diseases, in the cervical cellulitis and during the complications of sinusitis or mastoiditis. The foreign bodies (CE) are the most frequent cause of O.R.L emergencies. The complications depends of the location of the foreign: almost nonexistent if the CE is located in the nasal fossa or in the meatus acusticus externus, inconstant if CE is oropharyngeal or oesophageal. The complications may be fatal if CE is pharyngotracheal and are relevant to the exact location of CE which result in emergency behavior. The considered oesophageous lesions not due to CE are chemical burns and perforations; in emergency, hemorrhagic O.R.L. lesions only epistaxias are concerned; O.R.L. hemorrhage need to be studied with their specific causes.
The authors report 8 cases of youthful otosclerosis over 512 surgical otosclerosis cases. This study is compared for literature's datas: frequency comparable (1 to 1.6%), start age sometimes early, before 4 years for one case. The family's antecedents are quickly, but not always present. The clinical and audiometric study are detailed. In all cases one inner ear malformation (communication with cerebrospinal fluid) has been eliminated by one computer tomography. The treatment is often a long follow up, to operate in adolescent age, or adult. The surgery is earlier, when the hearing loss is fast. This surgery is classic and one hypertrophic stapedius platine is often found. The results are not as good as those in adults, but are correct.
This study was conducted in order to assess the activity of trimetazidine dosed at 60 mg/day in patients presenting degenerative loss of hearing. Ten centers participated in this multicenter double-blind placebo-controlled trial which spanned 6 months. Included were 251 patients (118 women, 133 men) presenting with pure perception bilateral symmetrical deafness concerning predominantly the acute frequency range. 228 patients terminated the study, including 115 in the trimetazidine group and 113 in the placebo group. The evolution over a 6-month treatment period was significantly better with trimetazidine as regards the following parameters: audibility as assessed by pure-tone audiometry, namely at the acute frequency range (p = 0.002), intelligibility as assessed by speech audiometry (p = 0.008), subjective evaluation of hearing loss and its impact on the patient's social life. Results confirm the value of trimetazidine hearing loss management, based on clinical, subjective criteria as well as audiometric ones. Parameters reflecting best trimetazidine's efficacy were intelligibility and the psychological/behavioral impact of the impairment, allowing for better social integration of the subject.
We observed a combination of nephronophthisis, tapetoretinal degeneration, vermian agenesis and encephalopathy in three first cousins. Juvenile nephronophthisis, the main inherited renal disease of childhood, is occasionally associated with a genetically linked disease involving the eyes and/or bone and/or liver and/or nervous system. We have assembled approximately one hundred cases of complex nephronophthisis. We discuss the various associations, among which the Senior syndrome (nephronophthisis + tapetoretinal degeneration) is the most frequent. The familial combination seen in our patients has apparently not been previously reported and seems to represent a new expression of the disease.
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The authors describe three case histories of auditory lesions involving the cortex or subcortex of the temporal lobes. In two of the cases there are minor lesions of the hemisphere producing an amusia without verbal deafness or agnosia of non-verbal sounds. In one of the two patients, the total transitory deafness makes the use of the term cortical deafness debatable. In the third case, a bilateral vascular lesion of the temporal lobes had produced a pure verbal deafness without loss of tone discrimination or loss of the capacity to recognise changes in rhythm or sound frequency. In these three patients in whom there was no anatomical verification, the data given by the scanner and the study of evoked cortical potentials recorded over the two cerebral hemispheres allowed a fairly good study of the correlations between the topography of the lesions and their semiotic consequences.
An opaque enema was carried out with Gastrografin. The patient was a 2-year-old French boy. As the enema progressed we saw the small mesenteric veins opacify: no significant consequence followed. This is the first report of such an incident.
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