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Biomedical subjects

P Romano

Publications and source records attributed to P Romano.

13 recordsLinked to original sources

[The Cerebral Function Monitor in intensive care].

The Monitor of Cerebral Function, the first apparatus designed for continual cerebral monitoring for prolonged periods, is used frequently as an aid during revival. Due to its ease of operation and its straight-forward displaying of the data, it can supply continual information on the state of cerebral activity. Wem used it in various situations where there was a risk of cerebral circulatory insufficiency. Besides this role in the prevention of emergency, we used the M.C.F. as a diagnostic tool in the assessment of brain death. An early confirmation of the presence of stage IV allows of a more efficient removal and grafting of the kidneys. Finally, we also use the M.C.F. in the study of abnormalities of behaviour in patients whose revival to consciousness is slow.

Brain

[Use of the Cerebral Function Monitor in the study of physiological sleep].

After a brief description of the different phases of physiological sleep, the reasons for employing a new appatus, the Monitor of Cerebral Function, are discussed. This instrument, the first designed for continual monitoring of cerebral activity may be employed in neurophysiology. The results obtained are presented, i.e. the demonstration of a perfect correlation between the Monitor of Cerebral Function recording and the polygraphic methods. The paradoxal and rapid phases of sleep are easily distinguished. The study of paradoxal sleep, both in physiology and in pharmacology, could profit greatly from the use of the MCF due to the great advantage of its ease of operation.

Adult

[Bacteriology of the atmosphere in microclimate tents].

Micro-climate tents (pulsed filtered air) are frequently used in burns departments. In the Surgical and Traumatological Intensive Care Unit of the Department of Anaesthesia and Intensive Care of the Henri Mondor Hospital, these tents are used in two types of indications: --placing of a tent over the head end of patients following tracheotomy with free spontaneous ventilation;--placing tents over irregular wounds. In these two categories of use, the aim is to isolate the zone under the tent by protecting it against secondary infection, but also to limit to this micro-climate any possible dissemination from the injured individual placed under the tent. Comparative study of the bacterial flora of the biotopes thus enclosed by micro-climate tents has been attempted.

Air Microbiology

[Bacteriological survey of the surgical and traumatology intensive care service at the Henri Mondor Hospital].

--A purely bacteriological presentation of the information on the infections of 567 patients hospitalized for 18 months (January 1977 to the end of 1978) in a resuscitation unit for cases of trauma. -- 975 organisms were isolated and identified. 75 p. 100 Gram negative bacilli. -- The various specimens are analysed. Lung infections were present in: 54.6 p. 100 -- urinary infections are rare, giving rise to 10 p. 100. One remarks the low number of septicaemias, only 29 or 5 p. 100 of those hospitalized compared with the 942 vascular catheters that were introduced and all bacteriologically tested.

Bacterial Infections

Biosynthesis of sulphur amino acids in Saccharomyces cerevisiae II. Analysis of suplhite-producing strains.

A number of strains of Saccharomyces which produce sulphite by sulphate reduction were examined from an enzymatic and genetic point of view. There are a number of mechanisms that regulate this activity. All of these mechanisms involve the sulphite-reducing activity. In the strains examined, reduced function as a result of mutation in the Sr-locus (affecting H2S-NADP oxidoreductase EC 1.8.1.2), repression of biosynthesis of the enzyme because of a mutation below the specific locus, and inhibition of the enzyme by endogenous factors were found to be responsible. The production of sulphite can also be connected with a complex state of heterozygosity. It is probably this multiplicity of biochemical and genetic mechanisms that accounts for the frequency with which the production of sulphite is observed in wild strains in nature.

Methionine

[Neuroplegia and extracorporeal circulation. Comparison between combinations of droperidol-phenoperidine and chlorprothixene-dextromoramide in cardiac surgery].

After a quick review of the physiopathology of extra-corporeal circulation, the value of the use of neuroplegic drugs in cardiac surgery is recalled by means of pharmacological arguments. The experimental differences existing between the combinations droperidol - phenoperidine and chlorportixene - dextromoramide, on the rate of flow and on the pressure of the perfusion, and on the esophago-rectal thermic gradients during E.C.C. is then demonstrated. Statistic calculation confirmed the superiority of chlorprotixene in the realm of tissue perfusion during E.C.C. under hypothermia.

Adult