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Biomedical subjects

P Roudebush

Publications and source records attributed to P Roudebush.

At least 19 recordsLinked to original sources

The histamine content of commercial pet foods.

The histamine contents of a range of North American commercial pet foods and pet food ingredients were determined by a spectrofluorometric technique. The change in histamine content of open cans of pet food stored in a refrigerator or at room temperature was also investigated. The histamine content of the pet foods examined ranged from a low of 0.16 microg/g in a liquid critical care diet to a high of 65.5 microg/g in a canned fish diet. The amount of histamine in the foods tested was insufficient to cause histamine toxicosis but it cannot be excluded that some of the foods contained sufficient histamine to cause idiosyncratic reactions in histamine-sensitive cats. Storage of opened cans of pet food, either under refrigeration or at room temperature, did not significantly increase the histamine content of most pet foods.

Journal Article↗

Showcase, a veterinary case authoring and presentation system.

Showcase is an instructional authoring and case presentation system for veterinary medicine. It is intended to permit instructors and students to deal with clinical case information in a dynamic and interactive way. The programs are distributed as "adware;" and, it is hoped, the case files will be freely shared and distributed.

Authorship↗

Laryngoscopy.

The larynx normally functions in vocalization, deglutition, and respiration. There is no substitute for direct laryngoscopy in animals suspected of having laryngeal disease. Clinical signs that should alert the veterinarian include cough, choking while eating or drinking, exertional cyanosis and syncope, noisy breathing, inspiratory dyspnea, stridor, and significant change in sound production. Controlled anesthesia is mandatory for animals with suspected laryngeal disease because many of these patients have compromised respiratory function. Laryngoscopy is used to note abnormalities in the shape, color, and motility of the larynx with special attention to correlating the movement of the arytenoid cartilages and vocal folds with the respiratory cycle.

Animals↗

Tracheobronchoscopy.

Fiberoptic tracheobronchoscopy is a safe and rewarding technique for the diagnosis and management of a wide spectrum of respiratory tract diseases. A nomenclature system has recently been developed that allows the systematic identification of canine endobronchial anatomy during bronchoscopy. This system results in an improved ability to communicate bronchoscopic findings and provides a basis for performing a thorough bronchoscopic examination. Complications of tracheobronchoscopy are uncommon, but patients must be carefully monitored during the procedure because complications may be severe and life-threatening when they occur. Special techniques enhance the diagnostic spectrum of bronchoscopy and include brush cytology, forceps biopsy, bacterial culture, transbronchial lung biopsy, transbronchial needle aspiration, and bronchoalveolar lavage.

Animals↗

Ketoconazole-induced changes in selected canine hormone concentrations.

The effects of administering ketoconazole at a high dosage (30 mg/kg of body weight/day) and at a low dosage (10 mg/kg/day) on steroidogenesis in the dog were compared. Ketoconazole significantly suppressed basal plasma cortisol concentrations (P = 0.001), cortisol responsiveness to ACTH (P = 0.002 to 0.005), and serum testosterone concentrations (P = 0.0005). The data indicated a rebound effect after ketoconazole treatment was stopped and that testosterone suppression was being overridden at lower ketoconazole doses. Plasma 17-alpha-hydroxyprogesterone concentrations (P = 0.0005) and serum progesterone concentrations (P = 0.014 to 0.003) were significantly increased during ketoconazole treatment. Aldosterone, 11-desoxycortisol, and 17-beta-estradiol concentrations did not change significantly during ketoconazole treatment.

17-alpha-Hydroxyprogesterone↗

Duodenal aspiration via flexible endoscope for diagnosis of giardiasis in a dog.

A 1-year-old male Pointer was admitted for evaluation of chronic diarrhea and mild weight loss. An aspirate of duodenal contents was obtained after infusing 0.9% Na Cl through a flexible endoscope passed into the proximal portion of the duodenum. Examination of the aspirated duodenal contents revealed a Giardia trophozoite, and the dog improved with metronidazole therapy. Duodenal aspiration via a flexible endoscope offers a new diagnostic technique for giardiasis.

Animals↗

Mycotic pneumonias.

Mycotic pneumonias are common problems seen in small companion animals because of the wide environmental distribution of fungi and their use of airborne spores for reproduction. This article outlines the important clinical features and pathogenesis of mycotic pneumonias and includes a detailed discussion of the therapeutic approach to patients with these infections.

Amphotericin B↗

Pleural effusion as a sequela to aelurostrongylosis in a cat.

A two-year-old domestic cat was admitted with dyspnea and coughing. Unilateral pleural effusion with characteristics of an eosinophilic exudate was demonstrated. A direct fecal smear was positive for Aelurostrongylus abstrussus larvae. Treatment with levamisole and fenbendazole was curative. Aelurostrongylosis should be suspected in any cat with dyspnea, coughing, or pleural effusion.

Animals↗

Lung sounds.

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Animals↗