[Legal and ethical problems in organ transplantation in children].
Explore the source record for details and available documents.
Biomedical subjects
Publications and source records attributed to P Royer.
Explore the source record for details and available documents.
In this retrospective study, the authors describe the clinical, histologic and laboratory features of 15 cases of chilblain or perniotic lupus. In winter, the patients (14 women, 1 man) develop chilblain-like lesions, chiefly in the toes (8 times) and fingers (11 times). Histologic features are identical to those of discoid lupus erythematosus. The damaged skin gives a positive fluorescent band test. Usually, these lesions occur in association with discoid lupus of the face. However, in 8 patients, they were the only cutaneous sign of lupus. This form of lupus can evolve to a systemic form, as was the case with 3 patients.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
The subject of this prospective study was to appreciate the natural history of 34 herniated lumbar nucleus pulposus after recovery excluding surgical or intra-discal therapy. First CT scan was performed when radicular pain was worst, second CT between 1 and 32 months after recovery (6 to 40 months after the first CT). After the first 18 months, 18 herniations decreased more than 50% (group I) and 7 less than 25% (group II). Most herniations of group II were large or middle sized and two narrowing of discs were observed between the two CT. Group II was made of small sized herniations and 4 discs out of 7 narrowed. Beyond 18 months, herniations decreased more than 75% excepted one being calcified. Decrease of herniations and of intra-discal pressure were observed in the study. Both could allow recovery.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
The potential short-term arrhythmogenic role of catheter-mediated electrical ablation was studied in 61 patients of mean age 44 years (range 15-80 years) who underwent this procedure for Wolff-Parkinson-White syndrome (36 patients) or ventricular tachycardia (VT, 25 patients). Continuous ECG monitoring was pursued during the 24 hours that preceded and followed ablation. Only bursts of 3 consecutive beats or more were considered significant. Recordings were performed with either a Hewlet Packard 78720 A arrhythmia recorder or a Holter readout system (Oxford Medilog 2, Marquette). In 36 patients with an accessory conduction pathway the 160 J were delivered at the annulus fibrosus cordis. Post-ablation recordings showed: VT bursts in 16 patients (17%); the bursts disappeared in every case before 3 days; in 3 patients the electrogram at the site of ablation was predominantly ventricular (p less than 0.05); frequent or subintrant attacks of reciprocal orthodromic rhythm (RR); in 3 cases RR began on simple variations of heart rate; it reflected a loss of the anterograde conduction hidden in the accessory pathway and required a second ablation; in 1 case RR initiated by VT bursts revealed the presence of a second accessory pathway; atrial tachycardia bursts, spontaneously resolved, in 4 patients (11%). No atrial fibrillation of flutter was recorded. In patients with VT ablation was delivered in the right ventricle (160 J, 9 patients) or in the left ventricle (240 J, 16 patients). The effects of ablation could only be interpreted in 21 patients who underwent 25 ablations.(ABSTRACT TRUNCATED AT 250 WORDS)
Explore the source record for details and available documents.
Hypotonia, neonatal respiratory distress with a chest wall deformity should arouse clinical suspicion to the diagnosis of primary hyperthyroidism. The most common signs at this age are hypercalcaemia, increased alkaline phosphatase, low TRPP and radiological changes especially in the hip. Radio-immunological assay of PTH and plasma concentrations of Vitamin D metabolites are important diagnostic aids but the interpretation of these results should take the clinical and familial context into consideration. Rapid bone structural changes, the resistance of the hypercalcaemia to usual therapeutic measures and the progression to rickets justify urgent surgical treatment. Nearly all cases are due to clear cell hyperplasia.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Two further cases of a meningioma of the ear simulating a glomus tumor are reported, pathological features in the first case leading to intensive discussion. Two such cases had been previously described in great detail in a paper published in 1977. In those patients, the differential diagnosis froma jugular glomus tumor was only established two and a half years later in one case, when excision was necessary because of an intracranial recurrence, and following-re-examination of all sections of jugular glomus tumors previously operated upon, in the other case. Factors enabling detection of meningiomas simulating glomus tumors were also discussed in the original report. Theses included discordance of clinical finding, -minimal signs on arteriography, -the primordial value of contrast computed tomography, -systematic alerting of the pathologist.
A 15 year old adolescent with Crohn's disease who received total parenteral nutrition for three months developed riboflavin deficiency. The aetiology, the clinical picture and the method of diagnosis of this unusual deficiency are reviewed. The importance of an adequate intake of vitamin B2 and the other B group vitamins, particularly in the malnourished, is emphasied.