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Biomedical subjects

P Ryals

Publications and source records attributed to P Ryals.

3 recordsLinked to original sources

The medical department in military operations other than war. Part II: Medical Civic Assistance Program in Southeast Asia.

It is a short trip by air from Bangkok, Thailand, to Phnom Penh, Cambodia, but a dramatic contrast. A Medical Civic Assistance Program (MEDCAP) visit was conducted in conjunction with Exercise Flash Canoe 97, the first U.S. Navy mission to Cambodia in more than 22 years. Nearly 3,000 patients were seen by the MEDCAP team members. Medical and dental care, medications, educational materials, and training were provided. The mission was an exceptional training opportunity for U.S. Medical Department personnel, who learned to function outside of the hospital and clinic environment and to deal with limited logistic backup, austere field conditions, a hostile environment, and an overwhelming number of patients, many of them with infectious diseases. Cambodia lacks public health infrastructure and has uncertain communications, difficult travel conditions, and an unstable political climate. Using the planning checklists described in Part I, the team completed the "in-country" part of the mission with minimal logistic and support problems, maximizing the effectiveness of the health care providers. The MEDCAP is an important instrument of U.S. foreign policy and friendship with other peoples.

Adolescent

Bronchial asthma.

Bronchial asthma is a very common disease afflicting 2 to 3 per cent of the general population. Attacks may be mild or life-threatening. Modern guidelines for diagnosis, therapy, and prognosis are presented in this article.

Acute Disease

Metabolic clearance of furosemide in the rat.

The effect of probenecid on the metabolic clerance of [35S]furosemide was examined in Sprague-Dawley rats by the single injection technique. Metabolic clearance was found to decrease from 1.74+/-0.11 ml/min in animals which received furosemide alone to 1.06+/-0.10 ml/min in animals which received both furosemide and probenecid. Estimation of urine and biliary clearance revealed that approximately two-thirds of the metabolic clearance was due to urinary clearance and one-third to biliary clearance, and that both decreased after probenecid administration. Thin-layer chromatographic studies indicated furosemide was metabolized by both liver and kidney but also secreted in unchanged form in urine, and that the proportion of unaltered furosemide to metabolite in urine was increased by probenecid. Further studies indicated that phenobarbital pretreatment had no effect on either hepatic or renal clearance of furosemide and that bile clearance was not altered by acute bilateral nephrectomy.

Animals