Biomedical subjects

P S Lindsey

Publications and source records attributed to P S Lindsey.

7 recordsLinked to original sources

PubMed1996

Anterior ischemic optic neuropathy after open heart operations.

BACKGROUND: The overall incidence of anterior ischemic optic neuropathy after open heart operations at the Lahey Clinic is less than 0.5%. However, during the 2-year period, March 1, 1990, to March 1, 1992, an increased incidence (8 of 602 patients or 1.3%) of this complication was observed. METHODS: A rigorous analysis was conducted of all 602 patients who underwent operation during this period. RESULTS: No preoperative risk factors were identified. The development of anterior ischemic optic neuropathy was associated with prolonged cardiopulmonary bypass time, low hematocrit levels, excessive perioperative body weight gain, and the use of epinephrine and amrinone. Other hypothetical risk factors include systemic hypothermia, anemia, increased intraocular pressure, and microembolization. Treatment options include the use of corticosteroid medications, reduction of intraocular pressure, and optic nerve fenestration, although recent evidence and our experience indicate that the fenestration procedure is of no benefit. CONCLUSIONS: Because all methods of treatment have had limited success, efforts to prevent this complication are of paramount importance.

Aged↗

PubMed1996

Bisecting a foldable acrylic intraocular lens for explantation.

We describe a method of explanting an implanted foldable acrylic intraocular lens (IOL) through a small incision at the time of primary implantation without enlarging the original small incision. This method of bisecting foldable IOLs in the anterior chamber is safe and preserves the advantages of the original small incision.

Acrylates↗

PubMed1983

Removal of scleral buckling elements. Causes and complications.

Fifty-three patients underwent removal of their scleral buckling elements in our operating rooms during a 25-year period. Of these, 18 patients suffered a retinal redetachment and two went on to phthisis. "Life-table" (survival) analysis showed that the risk of redetachment was 23% within the first 30 days after buckling element removal and 33% within 90 days. The cumulative risk of redetachment during a four-year period gradually increased to 47%. Factors that had a statistically significant association with redetachment included the degree of vitreous traction at the time of the original retinal detachment and the extent of the original detachment. Age, race, sex, preoperative condition, type of buckling element, and cause of buckling element removal did not have a statistically significant association with redetachment.

Adolescent↗

PubMed1983

Ultrastructure of epiretinal membrane causing retinal starfold.

A prominent posterior retinal "starfold" was seen in an eye with an extensive rhegmatogenous retinal detachment. The retina was reattached with a scleral buckling operation. The epiretinal membrane causing the starfold was later removed by vitreous surgery and was studied by electron microscopy, permitting the first such clinicopathologic correlation in a human eye. The membrane was composed of vitreous collagen, newly formed collagen, and cells. The cell types included retinal pigment epithelial (RPE) cells, fibrous astrocytes, and macrophages. The fibrous astrocytes and some of the RPE cells contained intracytoplasmic microfilaments of the type thought to be myofibrils. These may account for contraction of the membrane, causing the starfold configuration of the underlying and adjacent retina.

Cataract Extraction↗

PubMed1983

Persistent hyperplastic primary vitreous. Surgical treatment.

Instruments designed for pars plana vitrectomy can be used to manage selected complicated congenital cataracts such as those with persistent hyperplastic primary vitreous (PHPV). We have applied closed-eye vitrectomy techniques through a limbal approach in seven eyes with PHPV. A clear pupillary space was achieved in all cases and two eyes achieved useful postoperative vision. The management of children with complicated congenital cataracts, such as with PHPV, is discussed.

Cataract↗

PubMed1983

Management of persistent hyperplastic primary vitreous.

Instruments designed for pars plana vitrectomy can be used to manage selected complicated congenital cataracts such as those with persistent hyperplastic primary vitreous (PHPV). We have applied closed-eye vitrectomy techniques through a limbal approach in seven eyes with PHPV. A clear pupillary space was achieved in all cases and two of the seven eyes achieved useful vision. The management of children with complicated congenital cataracts such as those with PHPV is discussed.

Cataract↗

PubMed1981

Bilateral choroidal hemangiomas and facial nevus flammeus.

Two patients presented with the rare combination of bilateral diffuse choroidal hemangiomas and bilateral facial nevus flammeus. In one eye of one patient, an associated serous retinal detachment was treated with xenon arc photocoagulation in an attempt to delimit the subretinal fluid. Clinicians should be aware of the subtle clinical findings of diffuse choroidal hemangiomas as well as the possibility of bilateral occurrence. Early recognition and treatment may prevent progression of total retinal detachment and neovascular glaucoma.

Adolescent↗