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Biomedical subjects

P S Stack

Publications and source records attributed to P S Stack.

9 recordsLinked to original sources

Pap smears. Still a reliable screening tool for cervical cancer.

This is the second in a series of short articles on management of common problems primary care physicians encounter in the office setting. Written by members of postgraduate medicine's Editorial Council, these articles offer a personal perspective gleaned from hands-on experience plus review of the literature. Here, Dr Stack looks at recommendations for Pap smear screening. Although not infallible, the Pap smear has been invaluable in reducing the incidence of cervical cancer over the past 50 years. This article covers current standards as well as controversies and new technologies.

False Negative Reactions↗

Trichinosis. Still a public health threat.

Trichinosis remains a worldwide public health problem, although most US physicians have little or no experience with the disease. A history of exposure to raw or undercooked pork and findings of myopathy, eosinophilia, and periorbital edema are characteristic. The diagnosis can be confirmed with tissue biopsy or serodiagnostic testing. Mild infections respond to limited bed rest and use of analgesics and antipyretics. More severe cases can be treated effectively with corticosteroids and anthelminthics.

Adult↗

Methotrexate for urticarial vasculitis.

A patient with urticarial vasculitis unresponsive to all treatments except systemic corticosteroids responded completely to low-dose oral methotrexate, allowing withdrawal of corticosteroids. Methotrexate is a proven treatment for other immunologic diseases, and low doses seem to carry an acceptable safety profile. Its use in urticarial vasculitis may be appropriate in selected patients.

Adult↗

Ogilvie's syndrome. Would you recognize it?

Numerous conditions predispose to Ogilvie's syndrome, a process that mimics bowel obstruction. Characteristic radiographic findings of acute pseudo-obstruction include dilatation of the cecum and the remainder of the colon but not the small intestine. Treatment is individualized. Massive cecal dilatation carries the risk of cecal perforation and its attendant high mortality rate. Conservative therapies, such as nasogastric suction, gentle enemas, and use of a rectal tube, may be beneficial. Decompression by colonoscopy or other means may be necessary.

Aged↗