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P S Toledo

Publications and source records attributed to P S Toledo.

10 recordsLinked to original sources
PubMedDate not supplied

In vivo observation of tracheal microcirculation in dogs.

Tracheal microcirculation was studied in six healthy anesthetized adult mongrel dogs. A transparent balloon was used to apply pressure to the tracheal mucosa during observation of the microcirculation. Pressures of microvascular occlusion were measured using an electrically callibrated silicone, envelope placed on the observation balloon. The different vessel sizes were measured and classified using the operating microscope. Capillary occlusion pressures ranged from 10 to 40 msurements of tracheal diameter were performed. Progressive local and generalized dilatation occurred. Capillary occlusion pressure was lower in the more dilated specimens. The lower than expected occlusion pressures are thought to be a result of the tracheal dilatation and may be related to the administration of drugs or other factors.

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PubMedDate not supplied

Comparison of five types of tracheostomy tubes in the intubated trachea.

Recognition of excessive cuff pressures as a major factor in tracheal injury has prompted the development of different types of cuffed tracheostomy tubes. Five brands of tracheostomy tubes in common use are evaluated in anesthetized adult dogs. Visualization of interior tracheal conditions during spontaneous and positive pressure ventilation permits a dynamic study of the trachea and its interaction with each tube under varying conditions. The relationship between intracuff pressure and cuff-tracheal wall pressure is analyzed for each tube. The selection of the proper tracheostomy tube for a given clinical situation should consider: 1) the cuff pressure necessary to achieve minimal leak, 2) torque transmission, 3) the ability to monitor cuff-tracheal wall pressure as a function of intracuff pressure, and 4) simplicity of design for optimum clinical use. Tracheal expansion occurs in a predictable fashion in response to different stimuli. However, the role of expansion in the susceptibility of this organ to injury remains to be investigated.

Animals↗