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P S Wallace
Publications and source records attributed to P S Wallace.
Chicken CP49: significant or paltry? An evolutionary perspective.
The lens-specific intermediate filament (IF) proteins CP49 and filensin have been identified in a large number of evolutionary divergent species. In the chick lens both CP49 and filensin have been identified. Recently a unique variant of CP49, CP49ins has been identified. CP49ins contains an insertion of 49 amino acids in helix 1b giving it characteristics similar to the lamin-like cytoplasmic IF of invertebrates. The presence of this variant form in the chick lens poses some important questions about the co-assembly of the two CP49 forms and also the evolutionary relationship with invertebrate IF proteins.
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