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Biomedical subjects

P Salenius

Publications and source records attributed to P Salenius.

At least 19 recordsLinked to original sources

Factors affecting the results of surgery for chronic critical leg ischemia--a nationwide survey. Finnvasc Study Group.

PURPOSE: To assess the factors affecting immediate outcome of surgery for chronic critical leg ischemia, especially the influence of surgeon's caseload and hospital volume. METHODS: The data of Finnvasc registry were retrospectively analyzed. A total of 11,747 surgical vascular reconstructions included 1,761 operations for chronic critical leg ischemia during 1991 to 1994. RESULTS: The 30-day postoperative leg amputation rate was 7.5% and the mortality rate 4.7%. Diabetes, previous vascular surgery or amputation, preoperative ulcer or gangrene, a surgeon's annual caseload fewer than 10 operations, and hospital volume fewer than 20 operations for chronic critical leg ischemia adversely affected amputation rates. The presence of coronary artery disease and renal dysfunction increased postoperative mortality rates. Both amputation rates and postoperative mortality rates were affected by the type of procedure. CONCLUSIONS: A surgeon's caseload and hospital volume affect amputation rate, but not mortality rate, in patients operated for chronic critical leg ischemia.

Aged↗

Postero-lateral spine fusion. A 1-4-year follow-up of 80 consecutive patients.

We analysed 80 consecutive patients with postero-lateral spine fusion performed during the years 1972-1976. Thirty-seven were women and 43 men, the mean age being 30 (14-54) years. In 73 cases the fusion was performed because of spondylolysis and spondylolisthesis and in seven because of some other form of painful instability. Preoperatively, all patients had pain in normal activities and 63 at rest. At the 1-5-year follow-up, eight patients were pain-free, while 69 had stress pain and 35 pain at rest. The reduction of pain was significant; 51 patients considered themselves improved, 18 unchanged and 10 worse. Twelve fusions united in less than 2 months, eight after more than 4 months, and two failed to unite. Patients under 20 years did better than older patients. The result was better when the fusion united within 4 months and also when the bone transplants were properly placed. We conclude that postero-lateral spine fusion can be advocated as treatment of painful spondylolisthesis and sometimes in low-back instability in younger patients.

Adolescent↗

Proximal tibial osteotomy in the treatment of osteoarthritis of the knee.

A long-term follow-up study is presented of 162 patients who were treated for knee arthrosis with proximal tibial osteotomy, 10 of whom had undergone a bilateral operation. The average follow-up time was 8 years. Pre-operatively, varus deformity was found in the knees of 117 patients; 45 of them had valgus knees. In 142 knees curved osteotomy was performed and wedge osteotomy in 30. At follow-up, 33% of the patients were found to have no pain. Significant long-term improvement was achieved, as registered at the time of follow-up, in 80% of the patients, whereas in 11% pain remained unchanged. Better results were recorded in women than in men (P less than 0.01). In the present study, slightly better results were obtained statistically using curved osteotomy (P less than 0.05). Postoperative plaster sleeve immobilisation for approximately 6 weeks (10 weeks at the most) gave the best results. Internal fixation seemed unnecessary.

Adult↗

Histological changes in clinical half-joint allograft replacements.

Fourteen biopsies of cartilage and subchondral bone were taken from nine half-joint knee allografts 10 weeks to 8 years after the transplantation. Deep-frozen cadaver grafts were used to replace the defective half-joint after resection for bone tumour. The biopsies revealed a slow substitution of the dead grafted bone and cartilage. Subchondrally, signs of incorporation could be seen from 12 months on. The dead cartilage matrix degraded gradually and slow simultaneous regeneration was observed. Thus, fibrocartilage was seen on the articular surface of the graft at 12 months, chondrocytes were present at 18 months, but islands of hyaline cartilage were not seen earlier than 7 years after the transplantation. In accordance with the earlier clinical findings, the histological signs of rejection were minimal. The long-term result of half-joint allograft transplantation is obviously dependent on the cartilage component.

Adolescent↗

Spontaneous correction of severe tibiofemoral deformity in growing children.

The progress of pronounced varus and valgus deformities of the knees in 20 children were followed. The most pronounced varus deformity as 33 degrees and the most pronounced valgus deformity was 20 degrees. The tibiofemoral angle in growing children was measured on roentgenograms by drawing a longitudinal axis between the femoral and tibial diaphyseal cortices. Spontaneous correction was seen in all cases during the growth period.

Age Factors↗

Application of free autogenous fibular graft in the treatment of aggressive bone tumours of the distal end of the radius.

Long-term results of the application of free autogenous fibular graft in the treatment of aggressive bone tumours of the distal end of the radius are presented. Six patients underwent radical resection of the tumour including the articular surface of the distal radius during the period 1969 to 1978, the average follow-up time being 5 years. In one case the tumour was low grade chondrosarcoma, in three cases a giant cell tumour grade two to three and in the remaining two a hemangioma. Five to twelve cm of the distal radius was resected and the defect was replaced using the ipsilateral proximal part of the fibula as free graft. Osteosynthesis was performed end to end with a plate fixation, or side to side with screw fixation. At follow-up, the range of motion in the radiocarpal joint was normal or close to normal in each case and all patients had returned to work within 6 months of the operation. None of the patients presented a recidive of the tumour.

Adult↗

Allogeneic transplantation in low-grade malignant bone tumours. A new operative technique to avoid amputation.

A massive allografting of deep-frozen cadaver bone or hemi-joint was performed in 11 patients with tumours which were diagnosed as aggressive, low-grade malignancies. One patient died from a pre-existing hepatic insufficiency. The other 10 patients have been followed up from 1 to 8 years. These patients received two bone grafts and eight hemi-joint grafts around the knee joint. The operative procedure consisted of fixation of the graft by stable osteosynthesis, surrounding the graft-host junction with an autogeneic iliac chips cuff and, in cases of hemi-joint grafts, reconstruction of the ligaments. X-ray, scintigraphy and biopsy were used to judge the incorporation of the graft. The patients had to be prepared to face a considerable morbidity with long non-weight-bearing periods and possibly further operations. A full restitution of function was achieved in the bone graft cases. The patients with hemi-joint grafts were also able to retain their limb with a good or satisfactory function. No metastases or recurrences were experienced. The allograft procedure appears to be useful for younger adults, whose long life expectancy makes this operation justifiable, although the fate of cartilage still is unpredictable.

Adolescent↗

Arthrography of the hip in the diagnosis of postoperative painful conditions after total hip replacement.

Arthrography of the artificial hip joint was performed postoperatively in 29 patients with pain after total hip replacement. In 23 cases the arthrographic findings were checked by operation and corresponded in 91%. In two arthrographies which did not give reliable results sinuses outside the thigh or a large pseudocapsule prevented a satisfactory performance of the arthrography. The unoperated patients had only mild discomfort or were considered a high risk for reoperation; they were treated with physiotherapy and medication. As a result of this investigation arthrography can be regarded as a highly reliable method of diagnosing the various causes of pains in the hip after total hip replacement.

Hip Joint↗

Total hip replacement by the Brunswik prosthesis. A preliminary report of 189 operations.

The results of 189 Brunswik total hip replacements, performed at the Orthopaedic Hospital of the Invalid Foundation, Helsinki, Finland, and followed up for 2-3 years, are presented. According to the modified system of Merle D'Aubigne & Postel excellent results were achieved in 11.1 per cent (21/189), good in 56.6 per cent (107/189) and fair in 27.5 per cent (52/189). The failure rate was 4.8 per cent (9/189) and consisted of four deep infections, four cases of aseptic loosening and one case of allergic loosening. Local complications occurred after primary operations in 7.5 per cent (12/159) and after revision operations in 26.7 per cent (8/30) and the difference was statistically significant (P less than 0.01). Among the complications, deep infections were encountered in 2.6 per cent (5/189), aseptic loosenings in 2.1 per cent (4/189). Other local complications were: ectopic ossification in 1.6 per cent (3/189), nerve injuries in 1.6 per cent (3/189), dislocations in 1.1 per cent (2/189), and peroperative fractures in 1.1 per cent (2/189). General complications were observed in 8.9 per cent (17/189). Thromboembolic complications were only seen in 2.6 per cent (5/189). A possible explanation for this low figure was the early ambulation of the patients on the first postoperative day. No deaths related to the operation occurred.

Adult↗

Results of operative treatment of lumbar disc herniation. A survey of 886 patients.

Over a period of 6 years (1960-65), 886 patients were operated on for herniated lumbar disc. In 1971, 695 of these patients (78.5 per cent) answered a questionnaire. The material was analysed with the aid of a computer. Persons in the age groups 30-39 (38 per cent) and 40-49 (34 per cent) were most prone to develop sciatica. At operation the distribution of positive findings was found to be 5.7 per cent at level L3-4, 58.3 per cent at L4-5 and 36 per cent at L5-S1. Myelography with a water-soluble medium was performed preoperatively in all cases and gave a correct diagnosis of level in 90.2 per cent. The late results were good in 56 per cent of patients and 63 per cent returned to their former occupation.

Adolescent↗