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P Sane

Publications and source records attributed to P Sane.

17 recordsLinked to original sources

CT of pineal region tumors.

The computed tomographic (CT) features of pineal region tumors were analyzed in 60 histologically proven tumors. This is the largest reported series of histologically verified pineal region tumors studied with CT. The tumors were classified as germ-cell tumors, glial tumors, pineal parenchymal tumors, and meningiomas. Preenhancement germinomas revealed characteristically high-density areas with calcification; uniform enhancement was seen after injection of contrast material. When present, pineal calcification was engulfed by the tumor. Teratomas, present only in male patients, revealed areas of mixed densities (e.g., calcification and fatty areas) and did not show significant contrast enhancement. Spontaneous intraventricular rupture was noted in one case. Unlike other tumors, the original pineal calcification could be recognized in two-thirds of glioma cases and was displaced anteriorly and superiorly in most. Gliomas were hypodense to isodense on precontrast scans and enhanced in a nodular and a ring fashion. Benign pineal parenchymal tumors showed iso- to hyperdense areas with nodular enhancement after injection of contrast material. Pineoblastomas were well defined hyperdense masses without calcification on precontrast scans. After injection of contrast material, they showed well defined enhancement with occasional small, central lucencies. Meningiomas were hyperdense in most cases, uniformly enhanced in a homogeneous fashion, and showed a tentorial attachment.

Brain Neoplasms↗

Computed tomography of the carotid space and related cervical spaces. Part I: Anatomy.

The carotid space, parapharyngeal space, and paraspinal space are described. The carotid space is shown on computed tomography (CT) to be posterior to the parapharyngeal space and separated from it by the styloid apparatus. The paraspinal space is posterior to the carotid space and separated from it by the longus and anterior scalene muscles.

Humans↗

CT of the nasopharyngeal region. Normal and pathologic anatomy.

The soft tissue anatomy of the nasopharynx is presented in terms of deglutitional and masticatory muscle layers. Within this framework of analysis, computed tomography can detect relatively early soft tissue changes of nasopharyngeal carcinoma.

Deglutition↗

Computed tomography of the nasopharynx and related spaces. Part II: Pathology.

Malignant tumors of the nasopharynx were analyzed by region of origin and route of spread. Nasopharyngeal carcinomas produced early submucosal infiltration of the deglutitional muscle layer with enlargement of the levator palati muscle and lateral displacement of the parapharyngeal space. Serous otitis media was frequently associated, and the trigeminal nerve was occasionally involved. Intracranial extension via the foramen lacerum was frequent. Metastases to the infratemporal fossa produced early involvement of the masticatory muscle layer with medial displacement of the parapharyngeal space. Adenoid cystic carcinomas showed late but disproportionate involvement of the sphenoid sinus. Chordomas extended into the retropharyngeal soft tissues via the petro-occipital fissure. Maxillary sinus carcinomas, which were very large at the time of presentation and impinged on the nasopharynx, showed extensive destruction of the pterygoid plates.

Carcinoma, Adenoid Cystic↗

Computed tomography of the nasopharynx and related spaces. Part I: Anatomy.

The normal computed tomographic anatomy of the nasopharynx and pterygopalatine and infratemporal fossae is analyzed. Particular attention is given to the distinction between deglutitional and masticatory muscles. The relations of the palatal muscles to the eustachian tube are described in detail. Those soft-tissue features that, when they deviate from normal, can provide early detection of nasopharyngeal lesions are emphasized.

Humans↗

Computed tomography of cerebellar hemangioblastomas.

Ten patients with proven cerebellar hemangioblastomas were studied by computed tomography (CT). Angiography was obtained in seven cases. Eight patients had a cyst and a nodule, one presented with a nodule only, and one with a cyst only. Some morphological features on CT were found particularly helpful in establishing the histological diagnosis of this tumor. All cysts in this series had either a nonenhancing wall or a thin, discontinuous enhancement rim. The remarkable thinness of the cyst is a helpful feature in differentiating between hemangioblastomas and ring enhancement due to metastases. All hemangioblastoma nodules are near the pia, particularly the tentorial surface or the occipital surface of the cerebellum. The nodules in this series were isodense with brain before and enhanced significantly after contrast medium injection, matching or exceeding the density of the straight sinus. In three cases, a large vessel leading to the nodule could be identified on CT. In only one of 10 cases was there a central lucency in the enhancing nodule. The CT density of the hemangioblastoma cyst correlated with the size of the nodule, i.e., the larger the nodule, the denser the cyst on precontrast studies. Compared to cerebellar astrocytomas, hemangioblastomas are not calcified and tend to have relatively small nodule associated with a large cyst. For a given size cyst, the nodule in an astrocytoma is usually larger.

Adult↗

Computed tomography of cerebral syphilis.

The computed tomographic findings in two patients with clinical and laboratory evidence of neurosyphilis are reported. Two patterns were described, one with pronounced lucency of the white matter and the other with multiple infarctions of unusual distribution.

Aged↗

Rupture of intracranial aneurysm during computerized tomography.

A computerized tomographic (CT) scan was performed on a patient with a suspected paraseller mass. Coincident with contrast injection, an unusual and distinctive "starburst" pattern appeared in the right parasellar region and was associated with sudden deterioration in the patient's condition. Subsequent CT and necropsy confirmed a ruptured aneurysm at the suspected site with a large subarachnoid hemorrhage. To our knowledge, this unusual CT picture of a rupturing intracranial aneurysm has not been previously illustrated.

Aged↗

The embolization of vascular malformations of the spinal cord with low-viscosity silicone rubber.

Development of the low-viscosity silicone rubber has made possible the successful embolization and complete obliteration of 9 out of 11 vascular malformations of the spinal cord treated with this material. The procedure is particularly useful in patients where the malformation is fed by a limited number of posterior radicular feeders without any supply from the anterior spinal artery. One patient with a supply from the anterior spinal artery. One patient with a supply from both anterior and posterior feeders was successfully embolized after a temporary occlusion of the anterior spinal radicular feeder. Seven patients out of 11 embolized with silicone rubber showed a clinical improvement of their signs and symptoms.

Adult↗

Computed tomography of primitive neuroectodermal tumors.

The primitive neuroectodermal tumor is a neoplasm of young individuals that occurs predominantly in the supratentorial compartment. It appears on computed tomography as a bulky mass, often with calcification with predominantly homogeneous enhancement but on occasion with cystic or necrotic areas. Cerebrospinal fluid seeding was observed in more than half the cases in our series. The patients had a short survival period (7-24 months). Despite surgery, radiation, and chemotherapy, further growth of this tumor has not been prevented.

Adolescent↗

In vivo NMR imaging of tissue sodium in the intact cat before and after acute cerebral stroke.

The first in vivo nuclear magnetic resonance (NMR) images of tissue sodium in the intact animal are presented. The distribution of sodium in the normal cat's head is described. An experimental stroke was surgically induced. Sodium NMR imaging showed a pronounced focal increase in cerebral sodium concentration 9 hr after ligation of the middle cerebral artery. The method appears to be very sensitive for early detection of infarction. The measured increase in the regional sodium NMR signal probably reflects both a true increase in concentration of brain sodium and an increased NMR visibility of the sodium nucleus in the region of the infarction.

Animals↗

Computed tomography of the anteverted internal auditory canal.

A symmetric variation in the course of the internal auditory canals, visualized best on axial computed tomographic views with thin sections, was observed in three of 75 patients examined mainly for hearing, vestibular, and facial nerve dysfunction. The incidence may be lower in an unselected population. In coronal section, with either pluridirectional or computed tomography, an anteverted internal auditory canal may mimic the normal configuration of "medial narrowing" because of the effect of partial sectioning of an angled cylinder with a thin beam. The pathologic significance of this finding is uncertain. In the three cases reported, it was associated with adult-onset uni- or bilateral hearing loss. Vestibular function may be compromised but may not be symptomatic. Facial nerve function was not impaired.

Adult↗

Patterns of spinal cord atrophy by metrizamide CT.

Forty patients with cervical myelopathy underwent high-resolution computed tomography (CT) with intrathecal administration of metrizamide for evaluation of cervical spinal cord atrophy. Thirty of them showed evidence of either focal atrophic distortion or generalized accentuation of the anatomic surface features of the spinal cord. Patients with a Chiari malformation or syringomyelia were excluded. The characteristic features in cervical spondylosis and canal deformity include flattening of the ventral surface of the cord, central infolding, beaking of the lateral funiculi, and wasting of the dorsal surface of the cord. Patients with motor neuron disease showed a combination of anterolateral and posterolateral atrophy reflecting underlying degeneration of the anterior horn cells and/or corticospinal tracts, respectively. Those with monomelic motor neuron disease had a striking ipsilateral hemiatrophy of the spinal cord. Among those presenting with spastic paraparesis, seven with clinically definite multiple sclerosis showed diffuse atrophy or focal degeneration due to a localized plaque of demyelination. Two cases of cord neoplasm showed atrophy secondary to ascending or descending degeneration of the long tracts.

Atrophy↗

Computed tomography of the cervical lymph nodes: use of intravenous contrast enhancement.

Intravenous contrast administration increases the sensitivity of computed tomographic scanning for enlarged cervical lymph nodes but requires a detailed knowledge of neck anatomy, especially in order to distinguish certain normal vessels from involved nodal groups. Along the collar chain, relations between the parotid and submandibular salivary glands and the posterior and anterior facial veins and facial artery are analyzed. The digastric muscle is defined as a transitional landmark between collar and deep cervical nodes. Along the deep cervical chain, emphasis is on the internal jugular vein, its variability in size, and its relations to the anterior scalene and omohyoid muscles.

Humans↗