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Biomedical subjects

P Sauthier

Publications and source records attributed to P Sauthier.

11 recordsLinked to original sources

[Cervical cancer screening: current status and perspectives].

Cervical cancer screening with Pap cytology has effectively reduced the incidence of morbidity and mortality from invasive cervical cancer. However, Pap cytology has important limitation and is not completely protective. Invasive cervical cancers are still diagnosed and main reasons are an insufficient coverage rate and presence of false-negative results. HPV testing has greater sensitivity than Pap cytology for detecting high-grade lesions and cancer and is clearly one of the most promising new screening tools. It has the potential to improve cervical cancer screening effectiveness. The aim of our study was to discuss the current situation of cervical cancer screening in Switzerland, limitations of Pap cytology as well as the benefice expected with HPV testing and vaccienes.

Europe↗

[Liver transplantation and pregnancy: 1994 perspectives].

The authors report a case of pregnancy in a 24-year-old, gravida-3, para-1 patient who had previously undergone liver transplantation for alveolar echinococcosis. Pregnancy and delivery were uneventful with no obstetrical or liver complications. Pregnancy seems to have little effect on liver transplants and rejection is seldom observed. Primary maternal complications are hypertension, preeclampsia, anemia and hyperbilirubinemia. Primary fetal complications include premature delivery and growth retardation. The mode of delivery depends on the obstetrical situation. Cyclosporin may be used during pregnancy. The risk of breastfeeding has not been clearly established. Pregnancy after liver transplantation is possible after 9 to 12 months but requires strict multidisciplinary surveillance. Barrier methods remain the preferred method of contraception for liver transplant patients.

Adult↗

[Value of penis endoscopy in sexual partners of women with condylomatous or dysplastic lesions].

TYPE OF STUDY: A retrospective study of 532 male sexual partners of patients who were examined for condylomatous or dysplasic lesions of the lower genital tract between January 1990 and June 1993. AIM: To evaluate the balanoscopy examination. The value of this examination for the follow-up of papilloma virus and dysplasic lesions in women. METHOD: Balanoscopy was performed after application of acetic acid (5%). Lesions were treated with viralytic agents or by CO2 laser destruction. Computer analysis of the data from the microscopic examination and treatment in partners was performed. MAIN RESULTS: Globally, peniscopy revealed a papilloma virus lesion in 43.3% of the cases. Nevertheless, for infectious lesions (condylomas) in women, 63% of the women had a papilloma virus lesions. CONCLUSION: Severe dysplasia of the penis is rare in our geographical area and balanoscopy is useful for the eradication of sexually transmitted diseases, sometimes for oncological examinations and to decrease the incidence of recurrent condylomatous or dysplasic lesions in women partners. Globally, the results are disappointing since the rate of recurrence was similar whether or not the male partner had been examined. The only difference was in case of rapid effective treatment in the partner which was obtained in 27% of the partners.

Adult↗

[Current indications for colposcopic examination].

OBJECTIVE: It has become necessary to set out exactly the indications for colposcopic examination and to improve out-patient therapy. A response has been made to the ever increasing pre-cancerous pathological conditions of the lower genital tract. TYPE OF STUDY: A review of the pathological conditions of the lower genital tract has led to colposcopic examinations being carried out to work out how far grounded its indications are. The authors particularly lead to the future for colposcopy and histology of so called "atypical" cytology. MATERIAL: A review of the literature and a retrospective study of the agreement between the cytology and the histology in 1,454 patients who were examined and followed up at the centre for laparoscopy and colposcopy between 1.1.1987 and 31.12.1991. THE PRINCIPLE: A study of the information is being gathered about the cytological, colposcopic and histological diagnoses. PRINCIPLES RESULTS: Dysplasias diagnosed cytologically were confirmed in 95% of cases by colposcopic examination and by the results of directed biopsy. In over 90% cases of smears showing "atypical" cells the colposcopy confirmed the pathology that was found and in more than 85% of cases the histological examination confirmed a papillomavirus lesion or a dysplasia of the cervix or elsewhere in the lower genital tract. CONCLUSION: Over and above the indication for colposcopic examination, cytological dysplasias were found and to were condylomata of the lower genital tract or leukoplakia of the vulva, and one has to add "atypical" smears. Furthermore repeating a smear in cases of atypical cytology is useless, and can be deceptive. Systemic control of the vulva and vagina has to be carried out when the cervix is examined because there is a frequent association of dysplasic lesions and there is a possible presence of isolated extracervical lesions when cytologically pathological smears are found.

Ambulatory Care↗