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Biomedical subjects

P Savary

Publications and source records attributed to P Savary.

7 recordsLinked to original sources

[Vertigo of traumatic origin].

Patient referrals very frequently occur for ill-defined vertigo that appeared some months or even years after a trauma. These should not, however, be considered as cases of functional vertigo. The vertigo is very real, may last several years and constitute a genuine disorder. Such cases are amply described in the literature. Although we cannot perfectly explain the physiopathology, we should not conclude that these patients are not ill. In 50% of cases, we can evidence the signs with radiology and electro-nystagmography provided a properly established protocol is followed. The success of the treatment proposed can be evidenced by cervical electronystagmography.

Craniocerebral Trauma

Vocal and social situation of laryngectomees.

A summary of progress of surgery and rehabilitation showed that the vocal and social situation of the laryngectomee in the world is very poor. To improve this situation, a world survey on the state of laryngectomees and a world Congress in Quebec City in 1974 were organized. Consequently, a special section of l'Hotel-Dieu de Quebec was organized to stimulate the vocal rehabilitation of the laryngectomees, and the global statistics now show that the percentage of success has increased from 54% to 83%.

Humans

Hydrolysis of an aliphatic monoester in emulsion by swine pancreas lipase: influence of interfacial bile salts molecules upon reaction rate.

The accumulation of four bile salts at the interface between water and n-hexyl laurate is studied. Gibb's interfacial excesses of these salts are calculated, starting from interfacial tension measurements. At the same time, emulsions of the ester are treated by lipase and reactions rates are plotted against the bile salt concentrations present in the water phase of the emulsions. Inhibition by conjugated bile salts appear before the critical micellar concentration is approached. There is no defined relationship between this inhibition and the fraction of interfacial area covered by detergent molecules. In accordance with recent publication, the discussion suggests that the energy level of interfaces is important for lipase action and that, when interfacial tension becomes too small, lipase does not attach to interfaces and appears as inactive.

Animals

[Tympano-ossicular homografts].

Following a few European and American authors, we have undertaken tympano-ossicular homografts at the Hotel-Dieu de Quebec. The organization of the bank was achieved with many difficulties. We undertook our first surgical homografts in 1974, and 27 cases have since been performed. Our statistics are based on 19 cases. We obtained a perfect tympanic membrane in 17 cases, and 60 per cent of these have shown good improvement in hearing. This percentage is remarkable when one considers that we limited this procedure to cases for which all other techniques were bound to fail.

Audiometry

[Reconstructive laryngectomy].

Following a brief historical review of the sporadic attempts to improve the total laryngectomy, the author presents a technique for reconstructive laryngectomy. This technique should be restricted to one part of the cricoid and, according to certain modifications, to the free part of the epiglottis. Using these modifications, this technique allows the neck to be closed completely, thus avoiding a permanent tracheostomy. Relearning phonation and swallowing is spontaneous. Four cases are presented -- two successful. In the two failures, it was noted that one death was due to a hepatic deficiency and one to failure in relearning to swallow, which was attributable to senility.

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