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Biomedical subjects

P Scali

Publications and source records attributed to P Scali.

17 recordsLinked to original sources
PubMed1993

[Evaluation and performance of the follow-up in treated cancer of the breast].

Follow-up of breast cancer is not always the same. On the basis of a retrospective study on 92 patients who presented with a progressive disease, the authors assess the effectiveness of complementary examinations and propose a follow-up protocol: clinical, laboratory tests, consisting of ESR, gamma GT, alkaline phosphatases, CA 15.3 every six months (or even every 4 months for CA 15.3) and radiological follow-up consisting of mammography and chest X-ray every year. Other examinations may also be prescribed if any change is detected by any of the tests listed above. The authors consider that this approach constitutes a balance between the minimalist and maximalist attitudes, and one which corresponds to the physician's duty to his patient.

Bone Neoplasms↗
PubMed1992

[Hyperplastic lesions of the high risk breast. Definitions, diagnostic and therapeutic problems].

It has become possible to select from the framework of those women who have epithelial proliferations a group that are at high risk. This has been achieved by bringing together methods employed in the fields of defining better what are lesions of the breast, in assessing what are the best ways early detection of cancer of the breast and in epidemiological researches. The precise significance of these lesions in the absence of sufficiently reliable biological parameters is still problematic and their future still uncertain. Their relationship to invasive cancer is far from being constant, but it is possible for them to regress spontaneously. There are still limits between the results obtained in experimental animals and in human beings but as yet there has been no medical treatment that can be claimed to be a certain way of avoiding proliferative activity in these mastopathies. Surgery is also often poorly adapted to this kind of situation. In view of this, the choice of therapy is often difficult and has to be tailored to each case.

Biopsy↗
PubMed1989

[Diagnosis and treatment of epithelial cancer of the ovary. Apropos of 102 cases].

This is a retrospective study including 102 cases records of female patients presenting with epithelial carcinoma of the ovary. Survival, as in the other series, depended upon the stage of the cancer at the time of diagnosis, mean survival rates being 77.1, 57.7, 26.6 and 19.3 for stages I, II, III and IV respectively. However, most of all, survival was related to the quantity of remanent tumoral tissue following the initial laparotomy. The 5-year survival rates were 84%, 42% and 10% when there was no residual tumor, when the latter measured less than 2 cm, and more than 2 cm, respectively. In contradistinction to what is generally found in such studies, the diagnosis here was established at earlier stages, since 53% of the cases of interest were female patients with stage I or II carcinoma. The chief argument, therefore, is based on the methods of early diagnosis and, judging from what is generally admitted in literature, on the place of extended surgery.

Adult↗
PubMed1976

[Indications and results of ileal neobladder during the development of cervix uteri cancer. Study of 32 cases].

32 uretero-ileoplasties were carried out during the course of carcinoma of the uterine cervix, where therapeutic complications required an urinary by-pass operation. A trans-ileal by-pass to the skin ensured better renal function and comfort than that provided by a skin ureterostomy. The operation carried out in 20 cases after curative radiotherapy,.remains possible with a reasonably low risk: 2 deaths. However, survival depends on the cancer. The operation is legitimate and advisable in urinary lesions due to treatment, but one wonders whether the operation is justified in cases where the carcinoma is inoperable. Present means of resuscitation made this surgery acceptable as far as the immediate risk is concerned and survival is undoubtedly comfortable. On may thus carry out again radical operations provided the lesions are limited and there is no fibropelvis after high dose cobalt-radiotherapy. But purely palliative trans-ileal urinary by-pass operations remain debatable. Their indications depend on the general condition of the patient, the desire of the surgeon to operate and the functional result of these palliative operations should not be lost by carrying out too radical an operation which will shorten survival time.

Dermatologic Surgical Procedures↗